| ITIS | "... on Earth as ___ in Heaven": 2 wds. |
| ITIS | "... on earth, as ___ in heaven" (Lord's Prayer line): 2 wds. |
| ITIS | "... you're being real?" |
| ITIS | "...Thy will be done on earth as __..." |
| ITIS | "Affirmative!" |
| ITIS | "Affirmative" |
| ITIS | "And that's the way ___": 2 wds. |
| ITIS | "Can confirm" |
| ITIS | "Can that be true?" |
| ITIS | "Correct" |
| ITIS | "Definitely" |
| ITIS | "Do you know what time ___?" |
| ITIS | "Do you know what time ___?": 2 wds. |
| ITIS | "Does Anybody Really Know What Time ___?" (Chicago song): 2 wds. |
| ITIS | "For real?" |
| ITIS | "For sure!" |
| ITIS | "How Sweet __!" |
| ITIS | "How Sweet ___ !" |
| ITIS | "How Sweet ___ (To Be Loved By You)" |
| ITIS | "How Sweet ___!" |
| ITIS | "How Sweet ___" |
| ITIS | "How Sweet ___" (James Taylor song): 2 wds. |
| ITIS | "How sweet __!" |
| ITIS | "How sweet __!'; Gleason's line |
| ITIS | "How sweet ___!" |
| ITIS | "How sweet ___!" (2 wds.) |
| ITIS | "How sweet ___!": 2 wds. |
| ITIS | "How sweet ____!" |
| ITIS | "How sweet —!" |
| ITIS | "How sweet___!" |
| ITIS | "Indeed!" |
| ITIS | "Indeed" |
| ITIS | "It is what __" |
| ITIS | "Let me tell you how ___": 2 wds. |
| ITIS | "No kidding" |
| ITIS | "No kidding" (2 wds.) |
| ITIS | "No kidding?" |
| ITIS | "No kidding?" (2 wds.) |
| ITIS | "No lie!" |
| ITIS | "Oh?" |
| ITIS | "Really?" |
| ITIS | "Really?" or "Really!" |
| ITIS | "See who ___" |
| ITIS | "Seriously?" |
| ITIS | "Sorry, that's the way __" |
| ITIS | "Tell it like ___" (be honest): 2 wds. |
| ITIS | "Tell it like___!" |
| ITIS | "Tell me like ___!" ("Give me the truth!"): 2 wds. |
| ITIS | "That a fact?" reply |
| ITIS | "That a fact?" response |
| ITIS | "That so?" |
| ITIS | "That so?" reply |
| ITIS | "That so?" response |
| ITIS | "That true?" |
| ITIS | "That's correct" |
| ITIS | "That's just the way ___" |
| ITIS | "That's just the way ___": 2 wds. |
| ITIS | "That's the truth" |
| ITIS | "True that" |
| ITIS | "True!" |
| ITIS | "True" |
| ITIS | "Verily" |
| ITIS | "Whoomp! (There __ __)" |
| ITIS | "Yes, correct" |
| ITIS | "Yes, indeed" |
| ITIS | "You bet!" |
| ITIS | "You know how ___ . . ." |
| ITIS | "You know how ___" |
| ITIS | "You know how ___": 2 wds. |
| ITIS | "You're totally right!" |
| ITIS | "__ __ Well With My Soul" |
| ITIS | "__ __ written ..." |
| ITIS | "__ the east, and Juliet is the sun" (Shakespeare) |
| ITIS | "__ what it is" |
| ITIS | "___ better to give than to receive": 2 wds. |
| ITIS | "___ better to keep your mouth closed ...": 2 wds. |
| ITIS | "___ certain" (Magic 8 Ball response) |
| ITIS | "___ more blessed to give than receive": 2 wds. |
| ITIS | "___ said ..." |
| ITIS | "___ what ___" ("Nothing I can do") |
| ITIS | "___ what ___" ("That's life") |
| ITIS | ''. . . but you know how __'' |
| ITIS | ''No kidding?'' |
| ITIS | ''No, really?'' |
| ITIS | ''Really?'' |
| ITIS | ''That's right!'' |
| ITIS | ''True story'' |
| ITIS | ''You know how __'' |
| ITIS | Affliction ending |
| ITIS | Ailment ender |
| ITIS | Ailment suffix |
| ITIS | Answer to "That so?" |
| ITIS | Brief confirmation |
| ITIS | Bruce Hornsby hit song "The Way ___" (2 wds.) |
| ITIS | Bruce Hornsby's "The Way ___" (2 wds.) |
| ITIS | Confirmation query |
| ITIS | End of an affliction |
| ITIS | End of an illness? |
| ITIS | Ending for senior |
| ITIS | Ending for sinus or senior |
| ITIS | Exclamation of confirmation |
| ITIS | Facetious suffix with senior |
| ITIS | Gleason's ''How sweet ___!'' |
| ITIS | How many a medical problem ends? |
| ITIS | How many diseases end |
| ITIS | Illness's end? |
| ITIS | Inflammation (Suff.) |
| ITIS | Inflammation suffix |
| ITIS | Inflammatory ending? |
| ITIS | Inflammatory suffix |
| ITIS | Irritation suffix |
| ITIS | Malady suffix |
| ITIS | Medical suffix |
| ITIS | Medical suffix that indicates inflammation |
| ITIS | Phrase that's often contracted … or suffix for something contracted |
| ITIS | Positive answer to "Is it really that good?": 2 wds. |
| ITIS | Possible answer to "Really?" |
| ITIS | Possible reply to "Really?" |
| ITIS | Reply to "Can this be true?" |
| ITIS | Reply to "Really?" |
| ITIS | Reply to "That a fact?" |
| ITIS | Reply to "That so?" |
| ITIS | Reply to 5-Down |
| ITIS | Reply to “That so?” |
| ITIS | Response to "Can this be?" |
| ITIS | Response to "That so?" |
| ITIS | See 29 Across |
| ITIS | Senior suffix |
| ITIS | Short statement or question |
| ITIS | Sinus suffix |
| ITIS | Start of a Stepquote |
| ITIS | Sufferer's suffix |
| ITIS | Suffix denoting inflammation |
| ITIS | Suffix for "senior" or "sinus" |
| ITIS | Suffix for senior |
| ITIS | Suffix for senior or sinus |
| ITIS | Suffix for “senior” |
| ITIS | Suffix used in medicine to name inflammations |
| ITIS | Suffix with adenoid |
| ITIS | Suffix with senior |
| ITIS | Suffix with sinus |
| ITIS | Suffix with sinus or senior |
| ITIS | Suffix with tonsil |
| ITIS | Swell suffix? |
| ITIS | Tell it like __ (be candid) |
| ITIS | Tell it like ___ |
| ITIS | Terse affirmation |
| ITIS | Terse assurance |
| ITIS | Terse confirmation |
| ITIS | The Beatles' "Yes _____" |
| ITIS | What surrounders |
| ITIS | With 4-Down, "Untrue!" |
| ITIS | Words before and after "what" |
| ITIS | Words on either side of "___ what ___" |
| ITIS | Words repeated in "___ what ___" |
| ITIS | Words said before and after "what" |
| ITIS | Words that can precede and follow "what" |
| ITIS | “And that’s the way —” |
| ITIS | “How sweet —!” |
| ITIS | “Mm-hmm” |
| ITIS | “Wait, really?” |
| ITIS | “Whoomp! (There ___)” (Tag Team hit) |
| ITIS | “Yes, indeed” |