| 100% | EDDIEMURPHY | 11 | "Coming to America" actor who played the title role in 1998's "Dr. Dolittle": 2 wds. |
| 63% | MATTHEWRHYS | 11 | "The Americans" actor who plays the title role in HBO's "Perry Mason": 2 wds. |
| 61% | TONYTODD | 8 | "Final Destination" actor who plays the title role in 16-Across: 2 wds. |
| 60% | HENRYFONDA | 10 | "On Golden Pond" actor who played the title role in 32-Across: 2 wds. |
| 59% | LIAMNEESON | 10 | "Schindler's List" actor who plays the title role in "Marlowe" (2 wds.) |
| 58% | JAREDLETO | 9 | "Blade Runner 2049" actor who plays the title role in "Morbius" (2 wds.) |
| 58% | DWAYNEJOHNSON | 13 | "Hobbs & Shaw" actor who plays the title role in "Black Adam" (2 wds.) |
| 57% | DEREKJACOBI | 11 | "The King's Speech" actor who plays the title role in the film "Cyrano de Bergerac" (2 wds.) |
| 57% | TARONEGERTON | 12 | "Rocketman" actor who plays the title role in the 2018 film "Robin Hood" (2 wds.) |
| 57% | RUSSELLCROWE | 12 | "Gladiator" actor who plays the title role in the 2010 film "Robin Hood" (2 wds.) |
| 56% | KEANUREEVES | 11 | "The Matrix Resurrections" actor who plays the title role in "John Wick: Chapter 4" (2 wds.) |
| 56% | DENNISQUAID | 11 | "Flight of the Phoenix" actor who plays the title role in 16-Across: 2 wds. |
| 55% | JOSEPH | 6 | & 14A Actor who played the title role in 1998 comedy-drama film Shakespeare in Love |
| 55% | HARRISONFORD | 12 | "The Fugitive" actor who plays the title role in "Indiana Jones and the Dial of Destiny" (2 wds.) |
| 55% | EDDIEMURPHY | 11 | "Coming 2 America" actor who played Doctor Dolittle in 1998 and 2001 films: 2 wds. |
| 55% | JULIAROBERTS | 12 | "Pretty Woman" actress who played the title role in 2000's "Erin Brockovich": 2 wds. |
| 55% | EWANMCGREGOR | 12 | "Beauty and the Beast" actor who plays the title role in the new movie "Christopher Robin": 2 wds. |
| 55% | WISEMAN | 7 | Joseph —, actor who played the title role in 1962 action film Dr No |
| 55% | MICHAELKEATON | 13 | "Mr. Mom" actor who played the title role in 40-Across (2 wds.) |
| 54% | PETERCUSHING | 12 | Actor who played the title role in 1965 sci-fi film Dr Who and the Daleks |
| 54% | RAMONRODRIGUEZ | 14 | "Charlie's Angels" actor who plays the title role on 16-Across: 2 wds. |
| 54% | RUSSELLCROWE | 12 | "Gladiator" actor who played the title boy's father in "Boy Erased": 2 wds. |
| 54% | EDDIEMURPHY | 11 | "Coming 2 America" actor who played seven roles in the 1996 hit film "The Nutty Professor": 2 wds. |
| 54% | ROBERTDOWNEYJR | 14 | "The Avengers" actor who played the title role in "Chaplin": 3 wds., abbr. |
| 54% | KELSEYGRAMMER | 13 | Actor who played Dr. Frasier Crane in "Frasier" and "Cheers", and hosted the 1998 Grammy Awards: 2 wds. |
| 54% | MICHAELCIMINO | 13 | "Annabelle Comes Home" actor who plays the newly out title character in "Love, Victor": 2 wds. |
| 53% | EVANS | 5 | Chris —, US actor who played the title role in 2011 action film Captain America: The First Avenger |
| 53% | ADAMSANDLER | 11 | "Grown Ups" actor who played the title boy's father in "That's My Boy": 2 wds. |
| 53% | STEVECARELL | 11 | "The Big Short" actor who played the title boy's father in "Beautiful Boy": 2 wds. |
| 53% | MIKEMYERS | 9 | "SNL" alum who played the title roles in the "Austin Powers" and "Shrek" movies: 2 wds. |