| 100% | DAVIDTENNANT | 12 | "Doctor Who" star who turns 50 in 2021 (2 wds.) |
| 92% | EWANMCGREGOR | 12 | "Star Wars" star who turns 50 in 2021 (2 wds.) |
| 91% | MARKWAHLBERG | 12 | "Boogie Nights" star who turns 50 in 2021 (2 wds.) |
| 69% | QUEENLATIFAH | 12 | Rapper/actress starring in 17-Across and 39-Across who turned 50 this month (2 wds.) |
| 64% | MIKEPIAZZA | 10 | MLB Hall of Famer who turns 50 in 2018 (2 wds.) |
| 64% | BARRYSANDERS | 12 | NFL Hall of Famer who turns 50 in 2018 (2 wds.) |
| 64% | GARYPAYTON | 10 | NBA Hall of Famer who turns 50 in 2018 (2 wds.) |
| 61% | JENNIFERHUDSON | 14 | "Dreamgirls" actress who starred as Aretha Franklin in the 2021 biopic "Respect": 2 wds. |
| 60% | TOMCRUISE | 9 | "Mission Impossible" star who turned down the lead role in the classic film "Footloose": 2 wds. |
| 59% | YUK | 3 | Mr. ___ (poison symbol who turned 50 in 2021) |
| 58% | MARIOLOPEZ | 10 | 16-Across and 34-Across star who turned 50 on October 10, 2023 (2 wds.) |
| 57% | KIRKDOUGLAS | 11 | Actor who turned 100 in 2016: 2 wds. |
| 57% | MARKWAHLBERG | 12 | "The Lovely Bones," 14-Across, and 29-Across star who turns 50 years old tomorrow (2 wds.) |
| 56% | CHRISPAUL | 9 | NBA star who was traded in 2011: 2 wds. |
| 56% | LEBRONJAMES | 11 | Basketball star who played himself in "Trainwreck": 2 wds. |
| 56% | PAULMCCARTNEY | 13 | Liverpudlian music superstar who turned 70 in 2012: 2 wds. |
| 56% | JULIAROBERTS | 12 | "Erin Brockovich" star who plays Heidi in "Homecoming": 2 wds. |
| 56% | BOBBYCANNAVALE | 14 | "Third Watch" star who plays Colin in "Homecoming": 2 wds. |
| 56% | CHRISTIANBALE | 13 | Actor who stars as Dick Cheney in "Vice": 2 wds. |
| 55% | CARRIEFISHER | 12 | "Star Wars" actress who played Carol Peterson in 50-Across: 2 wds. |
| 55% | DANIELCRAIG | 11 | "Skyfall" actor who turned 50 on March 2, 2018 (2 wds.) |
| 55% | AMBERHEARD | 10 | "Magic Mike XXL" star who plays Mera in "Aquaman": 2 wds. |
| 55% | ALILARTER | 9 | "Heroes" actress who stars alongside Sean Bean in "Legends": 2 wds. |
| 54% | DAVIDTENNANT | 12 | Scottish actor who starred in "Doctor Who" and "Good Omens": 2 wds. |
| 54% | NAOMIOSAKA | 10 | Japanese tennis player who won the Australian Open in 2021: 2 wds. |
| 54% | BRUCEWILLIS | 11 | "Red 2" actor who starred in "Die Hard": 2 wds. |
| 54% | HELENMIRREN | 11 | "Red 2" actress who starred in "The Queen": 2 wds. |
| 54% | MIKETYSON | 9 | Boxing star who played himself in "The Hangover": 2 wds. |
| 54% | JOHNMCENROE | 11 | Tennis star who played himself in "Mr. Deeds": 2 wds. |
| 54% | KRISTENSTEWART | 14 | "Twilight" star who plays Sabina in 16-Across: 2 wds. |