| 100% | WINONARYDER | 11 | "Edward Scissorhands" actress, who plays a lead role in "Stranger Things": 2 wds. |
| 64% | ELLIEKEMPER | 11 | Actress who plays the lead role in 12-/24-Across: 2 wds. |
| 59% | ELISABETHMOSS | 13 | American actress who plays the lead role of Offred in the series in 18a: 2 wds. |
| 57% | WINONARYDER | 11 | Actress who plays a grandmother who tells the story of why it always snows on Christmas in Lutz, Florida, in "Edward Scissorhands" (2 wds.) |
| 57% | AMYPOEHLER | 10 | Actress who played the role of Leslie Knope in "Parks and Recreation", a role she is best-known for: 2 wds. |
| 56% | RACHELMCADAMS | 13 | "Spotlight" actress who plays a surgeon in "Doctor Strange in the Multiverse of Madness" (2 wds.) |
| 56% | ANDERSON | 8 | Actress Gillian, who played a lead role in "The X-Files" |
| 56% | DENISERICHARDS | 14 | Actress who played a Bond Girl in "The World Is Not Enough" and appeared in a guest role in "Two and a Half Men": 2 wds. |
| 55% | MARGOTROBBIE | 12 | Actress who plays a fictional associate producer in "Bombshell": 2 wds. |
| 55% | SARAHPAULSON | 12 | "American Horror Story" actress who won the 2024 Best Leading Actress in a Play Tony for "Appropriate": 2 wds. |
| 54% | MARISATOMEI | 11 | "My Cousin Vinny" actress who plays a teacher in "Spare Parts": 2 wds. |
| 54% | CAREYMULLIGAN | 13 | "The Great Gatsby" actress who plays a feminist in 42-Across: 2 wds. |
| 54% | MERYLSTREEP | 11 | "Into the Woods" actress who plays a feminist in 42-Across: 2 wds. |
| 54% | TESSATHOMPSON | 13 | "Thor: Ragnarok" actress who plays a surveyor in "Annihilation": 2 wds. |
| 54% | NATALIEPORTMAN | 14 | "Black Swan" actress who plays a biologist in "Annihilation": 2 wds. |
| 54% | AUBREYPLAZA | 11 | Actress who plays a profane 14th-century nun in "The Little Hours": 2 wds. |
| 54% | GRACEKELLY | 10 | Actress who played a socialite in Hitchcock's "Dial M for Murder": 2 wds. |
| 54% | XOCHITLGOMEZ | 12 | "The Baby-Sitters Club" actress who plays a time-traveling teenager in "Doctor Strange in the Multiverse of Madness" (2 wds.) |
| 54% | KATHYBATES | 10 | Actress who plays a marijuana dispensary owner in the new Netflix comedy "Disjointed": 2 wds. |
| 53% | WINONARYDER | 11 | Actress who played Lydia Deetz in the 1988 film "Beetlejuice" and Joyce Byers on "Stranger Things" in 2019: 2 wds. |
| 53% | DIANNEWIEST | 11 | "Bullets Over Broadway" actress who plays a grandma on "Life in Pieces": 2 wds. |
| 53% | ALICEBRAGA | 10 | "The New Mutants" actress who plays a revolutionary in "The Suicide Squad": 2 wds. |
| 53% | WINONARYDER | 11 | "Stranger Things" actress who plays Lydia Deetz in "Beetlejuice Beetlejuice": 2 wds. |
| 53% | KRISTENSTEWART | 14 | Actress who played a vampire in 2012's "The Twilight Saga: Breaking Dawn — Part 2": 2 wds. |
| 52% | CRISTINMILIOTI | 14 | Actress who plays a wedding guest who's stuck in a time loop in 44-Across: 2 wds. |
| 52% | HELENMIRREN | 11 | "The Queen" actress who plays a retired intelligence agent in "The Thursday Murder Club": 2 wds. |
| 52% | FARRAHFAWCETT | 13 | "Charlie's Angels" actress who played a photographer nicknamed Beauty in "The Cannonball Run": 2 wds. |
| 52% | ZOESALDANA | 10 | "Avatar" actress who played a pirate in the first "Pirates of the Caribbean" film: 2 wds. |
| 52% | CAMERONDIAZ | 11 | "The Mask" actress who played a private investigator named Natalie in "Charlie's Angels": 2 wds. |
| 52% | VIOLADAVIS | 10 | "Fences" actress who plays a government official in "The Suicide Squad": 2 wds. |