| 100% | JAMESMCAVOY | 11 | "Glass" actor who plays Charles Xavier in "X-Men" films, including 41-Across (2 wds.) |
| 65% | PATRICKSTEWART | 14 | "Star Trek: The Next Generation" actor who played Charles Xavier in "X-Men": 2 wds. |
| 61% | SOPHIETURNER | 12 | "Game of Thrones" actress who plays Jean Grey in "X-Men" films, including 41-Across (2 wds.) |
| 56% | PATRICKSTEWART | 14 | Actor who has played Charles Xavier since the first "X-Men" film (2 wds.) |
| 53% | ERICBANA | 8 | Actor who played 32-Across in a 2003 film: 2 wds. |
| 53% | EDWARDNORTON | 12 | Actor who played 32-Across in a 2008 film: 2 wds. |
| 53% | GENEWILDER | 10 | Actor who played 31-/34-Across in a 1971 film: 2 wds. |
| 53% | JOHNNYDEPP | 10 | Actor who played 31-/34-Across in a 2005 film: 2 wds. |
| 53% | JUDELAW | 7 | Actor who plays 22-Across/41-Across in the 2009 film "Sherlock Holmes" (2 wds.) |
| 53% | DUSTINHOFFMAN | 13 | Actor who played 43-Across in the movie "All the President's Men": 2 wds. |
| 53% | SHAWNASHMORE | 12 | Actor who plays Iceman/Bobby Drake in the "X-Men" films (2 wds.) |
| 51% | JASONROBARDS | 12 | Actor who played 15-Across in the 1967 film "The St. Valentine's Day Massacre": 2 wds. |
| 50% | NICHOLASHOULT | 13 | Actor who plays Beast in "X-Men: Apocalypse": 2 wds. |
| 50% | OSCARISAAC | 10 | Actor who plays Apocalypse in "X-Men: Apocalypse": 2 wds. |
| 50% | TOMHOLLAND | 10 | Actor who plays Spider-Man in 16-Across: 2 wds. |
| 50% | JAMESMCAVOY | 11 | "X-Men: Apocalypse" actor who plays Kevin Crumb (The Beast) in "Glass": 2 wds. |
| 50% | IANMCKELLEN | 11 | Actor who played Gandalf in all three "Hobbit" films: 2 wds. |
| 50% | HUGHJACKMAN | 11 | Actor who played Wolverine in the "X-Men" series: 2 wds. |
| 50% | JOHNTRAVOLTA | 12 | "Saturday Night Fever" actor who played hit man Vincent Vega in the 1994 film "Pulp Fiction" (2 wds.) |
| 50% | BLAIRUNDERWOOD | 14 | "L.A. Law" actor who plays Charles James Walker in "Self Made": 2 wds. |
| 49% | NICHOLASHOULT | 13 | "X-Men: Days of Future Past" actor who plays Nux in 15-Across: 2 wds.. |
| 49% | DANIELCRAIG | 11 | Actor who plays Detective Benoit Blanc in the 2019 mystery film "Knives Out": 2 wds. |
| 49% | VALKILMER | 9 | Actor who played rock star Jim Morrison in the 1991 film "The Doors": 2 wds. |
| 49% | RAMIMALEK | 9 | Actor who played rock star Freddie Mercury in the 2018 film "Bohemian Rhapsody": 2 wds. |
| 49% | CHRISTIANBALE | 13 | Actor who played the magician Alfred Borden in the 2006 film "The Prestige": 2 wds. |
| 49% | NICOLASCAGE | 11 | Actor who plays Benjamin Franklin Gates in the "National Treasure" films: 2 wds. |
| 49% | IANMCKELLEN | 11 | Actor who played the "old" Magneto in the "X-Men" series: 2 wds. |
| 49% | NICHOLASHOULT | 13 | Actor who played the "young" Beast in the "X-Men" series: 2 wds. |
| 49% | DUSTINHOFFMAN | 13 | "Rain Man" actor who played "Babe" Levy in 18-Across: 2 wds. |
| 49% | BENEDICTWONG | 12 | "Doctor Strange" actor who plays Baron in "Gemini Man": 2 wds. |