| 100% | JAMESMCAVOY | 11 | "X-Men: Apocalypse" actor who plays a man with multiple personalities in 1-Across and 62-Across (2 wds.) |
| 66% | BRUCEWILLIS | 11 | "Die Hard" actor who plays a man with superhuman strength in "Unbreakable" and 62-Across (2 wds.) |
| 63% | SAMUELLJACKSON | 14 | "The Avengers" actor who plays a man with extremely fragile bones in "Unbreakable" and 62-Across (3 wds.) |
| 51% | ROBERTDUVALL | 12 | Oscar-winning actor who played a man in love with a tiny doll on "The Twilight Zone": 2 wds. |
| 50% | JOSEPHCOTTEN | 12 | Actor who played a reporter and friend of the title character in 17-Across: 2 wds. |
| 47% | JAMESMCAVOY | 11 | "X-Men: Apocalypse" actor who plays Kevin Crumb (The Beast) in "Glass": 2 wds. |
| 46% | VINCEVAUGHN | 11 | "Dodgeball" and "The Internship" actor who plays a killer who changes bodies with Millie in "Freaky" (2 wds.) |
| 46% | JAMESMCAVOY | 11 | "X-Men: Apocalypse" star who played the title character of 28-Across in a 2015 movie: 2 wds. |
| 46% | NICHOLASHOULT | 13 | "X-Men: Apocalypse" actor who plays Peter III of Russia in "The Great": 2 wds. |
| 46% | OSCARISAAC | 10 | Actor who plays Apocalypse in "X-Men: Apocalypse": 2 wds. |
| 46% | NICHOLASHOULT | 13 | Actor who plays Beast in "X-Men: Apocalypse": 2 wds. |
| 45% | PAULBETTANY | 11 | Actor who plays a powerful android in Marvel's "Avengers" films and on 44-Across (2 wds.) |
| 45% | RYANPHILLIPPE | 13 | "Damages" and "Shooter" actor who plays a former cop on 1-Across/65-Across (2 wds.) |
| 45% | LESLIENIELSEN | 13 | "Airplane!" actor who played a vampire in the comedy "Dracula: Dead and Loving It": 2 wds. |
| 45% | ALANRICKMAN | 11 | Actor who played Professor Snape and was a misunderstood character in "Harry Potter" series: 2 wds. |
| 45% | FREDASTAIRE | 11 | "Top Hat" actor who played a con man in "The Towering Inferno": 2 wds. |
| 44% | SAMROCKWELL | 11 | "Iron Man 2" actor who played a kidnapped tech genius in "Charlie's Angels": 2 wds. |
| 44% | VINDIESEL | 9 | "The Fast and Furious" actor who plays a Marine turned supersoldier in 42-Across (2 wds.) |
| 44% | CHRISPERFETTI | 13 | "Looking" actor who plays a history teacher and ally of 15-Across: 2 wds. |
| 44% | BRIANGERAGHTY | 13 | "Chicago Med" and "Chicago Fire" actor who plays a long-haul trucker on 1-Across/65-Across (2 wds.) |
| 44% | TOMMYKIRK | 9 | "Old Yeller" actor who played Wilby Daniels as a boy in 29-Across: 2 wds. |
| 44% | JUDDNELSON | 10 | Actor who played a high school delinquent in "The Breakfast Club" and a yuppie politician in "St. Elmo's Fire": 2 wds. |
| 44% | EMILIOESTEVEZ | 13 | Actor who played a high school jock in "The Breakfast Club" and a law student in "St. Elmo's Fire": 2 wds. |
| 44% | MICHAELKEATON | 13 | "Spotlight" actor who has played a Marvel supervillian in "Spider-Man: Homecoming" and a DC superhero in "Batman": 2 wds. |
| 44% | COLINFIRTH | 10 | "The King's Speech" actor who played painter Johannes Vermeer in "Girl With a Pearl Earring": 2 wds. |
| 44% | ASHTONKUTCHER | 13 | "Two and a Half Men" actor who played Michael Kelso on "That '70s Show": 2 wds. |
| 44% | ZACEFRON | 8 | Actor who plays a protégé of 15-Across in "The Greatest Showman": 2 wds. |
| 44% | TYESHERIDAN | 11 | "X-Men: Apocalypse" actor who plays Parzival in "Ready Player One" (2 wds.) |
| 43% | YULBRYNNER | 10 | Actor who won a Tony and an Oscar for playing King Mongkut in "The King and I": 2 wds. |
| 43% | SHAQUILLEONEAL | 14 | 7'1" actor who played a genie in "Kazaam": 2 wds. |