| 100% | JOHNNYDEPP | 10 | "Murder on the Orient Express" actor who plays retired detective Russell Poole in 47-Across (2 wds.) |
| 62% | ALBERTFINNEY | 12 | "Annie" actor who played Belgian detective Hercule Poirot in the 1974 film "Murder on the Orient Express": 2 wds. |
| 58% | LESLIEODOMJR | 12 | "Murder on the Orient Express" actor who played Aaron Burr in "Hamilton": 3 wds. |
| 54% | ALBERTFINNEY | 12 | Actor who played Hercule Poirot in the 1974 film "Murder on the Orient Express": 2 wds. |
| 54% | PENELOPECRUZ | 12 | "Murder on the Orient Express" actress who plays Laura Ferrari in "Ferrari" (2 wds.) |
| 54% | KENNETHBRANAGH | 14 | "Murder on the Orient Express" and 45-Across star who is the only actor to direct himself playing Hercule Poirot (2 wds.) |
| 53% | KENNETHBRANAGH | 14 | Actor who played Hercule Poirot in 2017's "Murder on the Orient Express" and 2022's "Death on the Nile": 2 wds. |
| 52% | KENNETHBRANAGH | 14 | "Murder on the Orient Express" (2017) star who is the only actor to direct himself playing Hercule Poirot (2 wds.) |
| 50% | ALBERTFINNEY | 12 | "Murder on the Orient Express" (1974) star who is the only actor to be nominated for an Oscar for playing Hercule Poirot (2 wds.) |
| 49% | INGRIDBERGMAN | 13 | "Casablanca" actress who played a Swedish missionary in "Murder on the Orient Express": 2 wds. |
| 48% | BENKINGSLEY | 11 | "Gandhi" actor who plays a retired psychiatrist in "The Thursday Murder Club": 2 wds. |
| 48% | JESSEWILLIAMS | 13 | "Grey's Anatomy" actor who plays a camera operator on "Only Murders in the Building" (2 wds.) |
| 48% | STEVEMARTIN | 11 | "Dirty Rotten Scoundrels" actor who plays Charles on "Only Murders in the Building" (2 wds.) |
| 48% | PIERCEBROSNAN | 13 | "Mamma Mia!" actor who plays a retired union activist in "The Thursday Murder Club": 2 wds. |
| 48% | LAURENBACALL | 12 | "Key Largo" actress who played an American widow in "Murder on the Orient Express": 2 wds. |
| 47% | MORRISCHESTNUT | 14 | Actor who plays the title character of 47-Across in a CBS series that premiered in January: 2 wds. |
| 47% | MARTINSHORT | 11 | "Three Amigos" actor who plays a Broadway director/true crime podcaster on "Only Murders in the Building" (2 wds.) |
| 46% | TERRYCREWS | 10 | Actor who plays Detective Jeffords in the sitcom "Brooklyn Nine-Nine": 2 wds. |
| 46% | FRANKIEMUNIZ | 12 | Actor who played child prodigy Malcolm on "Malcolm in the Middle": 2 wds. |
| 46% | KYLECHANDLER | 12 | Actor who plays Cathcart in the Hulu miniseries based on 39-Across's "Catch-22" (2 wds.) |
| 46% | ANTHONYMACKIE | 13 | Actor who plays Falcon in the Marvel Cinematic Universe and has been on "Black Mirror": 2 wds. |
| 46% | DANIELCRAIG | 11 | Actor who plays Detective Benoit Blanc in the 2019 mystery film "Knives Out": 2 wds. |
| 46% | JAMESGARNER | 11 | Actor who played a private detective in Los Angeles on "The Rockford Files" (2 wds.) |
| 46% | PETERUSTINOV | 12 | Actor who played Hercule Poirot in the 1978 film "Death on the Nile": 2 wds. |
| 46% | SPENCERTRACY | 12 | Actor who played the lawyer based on Clarence Darrow in 32-Across: 2 wds. |
| 46% | KENNETHBRANAGH | 14 | "Tenet" actor who plays Hercule Poirot in "Death on the Nile": 2 wds. |
| 45% | TAYLORKITSCH | 12 | "Friday Night Lights" actor who plays Paul Woodrugh on the latest season of "True Detective": 2 wds. |
| 45% | FREDRICMARCH | 12 | Actor who played the lawyer based on William Jennings Bryan in 32-Across: 2 wds. |
| 45% | ROBERTSEAN | 10 | With 25-Across, actor who played Dr. James Wilson (based on 47-Across) on the Fox series "House": 2 wds. |
| 45% | DANIELKALUUYA | 13 | Actor who plays W'Kabi in the Marvel Cinematic Universe and has been on "Black Mirror": 2 wds. |