| 100% | KNOT | 4 | "Shopaholic Ties the ___" (third novel in a series by Sophie Kinsella) |
| 52% | STORMOF | 7 | "A ___ Swords," third novel in the epic fantasy series "A Song of Ice and Fire" by George R.R. Martin: 2 wds. |
| 51% | CASCA | 5 | Roman soldier in a series of novels by Barry Sadler beginning with 1979's The Eternal Mercenary |
| 51% | GLINDAOFOZ | 10 | 1920 novel in a series by L Frank Baum |
| 45% | TWILIGHT | 8 | First book in a series of vampire novels by Stephenie Meyer |
| 45% | ATIMEFORMERCY | 13 | 2020 best seller that's the third novel in Grisham's Jake Brigance series: 4 wds. |
| 45% | EVEDUNCAN | 9 | Forensic sculptor in a series of novels by Iris Johansen (2 wds.) |
| 45% | LADIES | 6 | "The No. 1 ___ Detective Agency" (first novel in a mystery series by Alexander McCall Smith) |
| 44% | TESSMONAGHAN | 12 | Reporter-turned-investigator in a series of novels by 44-Across (2 wds.) |
| 44% | ARMANDGAMACHE | 13 | Chief inspector in a series of mystery novels by Louise Penny (2 wds.) |
| 44% | TESSMONAGHAN | 12 | Reporter-turned-investigator in a series of crime novels by 44-Across (2 wds.) |
| 43% | FEAST | 5 | "A ___ for Crows," fourth novel in the epic fantasy series by George R. R. Martin |
| 43% | DARKOFTHEMOON | 13 | First book in a series of novels by John Sandford featuring 46-Across (4 wds.) |
| 43% | ACLASHOFKINGS | 13 | Second novel in the epic fantasy series "A Song of Ice and Fire" by George R.R. Martin: 4 wds. |
| 43% | DIVINEJUSTICE | 13 | Fourth novel in a series featuring Oliver Stone and his group of political watchdogs called the Camel Club (2 wds.) |
| 43% | SIXTEEN | 7 | Next number in a series suggested by the starts of 17-, 27-, 46- and 60-Across |
| 43% | ADA | 3 | ___ Thorne, character played by Sophie Rundle in the TV series "Peaky Blinders" |
| 43% | BLUE | 4 | "Violets Are ___," seventh novel in the Alex Cross series by James Patterson |
| 43% | LONDONBRIDGES | 13 | Tenth novel in the Alex Cross series by James Patterson: 2 wds. |
| 42% | HEAVENSRIVER | 12 | Fourth novel in the "Bobiverse" science-fiction series by 32-Across (2 wds.) |
| 42% | FORWEAREMANY | 12 | Second novel in the "Bobiverse" science-fiction series by 32-Across (4 wds.) |
| 42% | THELAST | 7 | & 17D 1956 novel in The Chronicles of Narnia series by C S Lewis |
| 42% | DAWN | 4 | "The Voyage of the ___ Treader," third novel in the fantasy series "The Chronicles of Narnia" by C.S. Lewis |
| 41% | MYRONBOLITAR | 12 | Fictional basketball player-turned-sports agent who solves mysteries in a series of novels by 35-Across (2 wds.) |
| 41% | GLASSHOUSES | 11 | Most recent novel in the mystery series by 40-Across featuring 30-Across (2 wds.) |
| 41% | SHADOWTYRANTS | 13 | 2018 novel in the Oregon Files series by 18-Across and 39-Across (2 wds.) |
| 41% | BFG | 3 | "The ___," children's novel written by Roald Dahl in 1982 about a young girl named Sophie who meets a colossal man |
| 41% | LADY | 4 | "___ in the Lake" (Apple TV+ series based on a Laura Lippman novel) |