| 100% | JOHNLITHGOW | 11 | 1996, 1997, and 1999 Emmy winner, Outstanding Lead Actor in a Comedy Series (for "3rd Rock From the Sun"): 2 wds. |
| 56% | ERICMCCORMACK | 13 | 2001 Emmy winner, Outstanding Lead Actor in a Comedy Series (for "Will & Grace"): 2 wds. |
| 53% | DAMIANLEWIS | 11 | Winner of the 2012 Emmy for Outstanding Lead Actor in a Drama Series for "Homeland": 2 wds. |
| 53% | JEFFDANIELS | 11 | Winner of the 2013 Emmy for Outstanding Lead Actor in a Drama Series for "The Newsroom": 2 wds. |
| 53% | BRYANCRANSTON | 13 | Winner of the 2014 Emmy for Outstanding Lead Actor in a Drama Series for "Breaking Bad": 2 wds. |
| 51% | JUDDHIRSCH | 10 | 1981 Emmy winner for "Taxi" (Outstanding Lead Actor In a Comedy Series): 2 wds. |
| 51% | JASONSUDEIKIS | 13 | "Ted Lasso" actor who won the 2021 Emmy for Outstanding Lead Actor in a Comedy Series: 2 wds. |
| 51% | DONALDGLOVER | 12 | Emmy winner for Outstanding Lead Actor in a Comedy for "Atlanta": 2 wds. |
| 50% | EUGENELEVY | 10 | "Schitt's Creek" star who won the 2020 Emmy for Outstanding Lead Actor in a Comedy Series: 2 wds. |
| 50% | MICHAELJFOX | 11 | 2000 Emmy winner, Outstanding Lead Actor in a Comedy Series (for "Spin City"): 3 wds. |
| 49% | DONALDGLOVER | 12 | Actor who won the Emmy for Outstanding Lead Actor in a Comedy for "Atlanta": 2 wds. |
| 48% | EUGENELEVY | 10 | Former SCTV regular who won the 2020 Emmy Award for Outstanding Lead Actor in a Comedy Series for playing Johnny Rose on 46-Across (2 wds.) |
| 47% | RAYROMANO | 9 | 2002 Emmy winner for Outstanding Lead Actor in a Comedy Series |
| 46% | LEVY | 4 | Eugene ___, actor from 45a who won the Emmy for Outstanding Lead Actor in a Comedy Series in 2020 |
| 46% | JEREMYSTRONG | 12 | "Succession" star who won the 2020 Emmy for Outstanding Lead Actor in a Drama Series: 2 wds. |
| 45% | JOSHOCONNOR | 11 | "The Crown" actor who won the 2021 Emmy for Outstanding Lead Actor in a Drama Series: 2 wds. |
| 45% | VIOLADAVIS | 10 | Winner of the 2015 Primetime Emmy Award for Outstanding Lead Actress in a Drama Series: 2 wds. |
| 44% | NICOLEKIDMAN | 12 | Emmy winner for Outstanding Lead Actress in a Limited Series for "Big Little Lies": 2 wds. |
| 43% | JOHNLITHGOW | 11 | "3rd Rock From the Sun" actor who won a Tony Award for "Sweet Smell of Success": 2 wds. |
| 43% | ELISABETHMOSS | 13 | 2017 Outstanding Lead Actress in a Drama Series Emmy winner for her role on "The Handmaid's Tale" (2 wds.) |
| 43% | ALLISONJANNEY | 13 | 2014 and 2015 winner of the Emmy for Outstanding Supporting Actress in a Comedy for "Mom": 2 wds. |
| 42% | MATTHEWRHYS | 11 | "The Americans" actor nominated for 2017's Outstanding Lead Actor in a Drama Series Emmy (2 wds.) |
| 42% | EDIE | 4 | 2010 Outstanding Lead Actress in a Comedy Series Emmy winner for Nurse Jackie |
| 42% | BALDWIN | 7 | Alec ___, actor who won the Emmy for Outstanding Lead Actor in a Comedy for "30 Rock" |
| 42% | AHMED | 5 | Riz —, 2017 Emmy Award for Outstanding Lead Actor in a Limited Series or Movie winner for The Night Of |
| 42% | CATHERINEOHARA | 14 | Former SCTV regular who won the 2020 Emmy Award for Outstanding Lead Actress in a Comedy Series for playing Moira Rose on 46-Across (2 wds.) |
| 41% | GERALDMCRANEY | 13 | Actor who won the 2017 Emmy for Outstanding Guest Actor in a Drama Series for playing the obstetrician who delivered Kevin and Kate in NBC's "This Is Us" (2 wds.) |
| 41% | ELISABETHMOSS | 13 | Emmy winner for Outstanding Lead Actress in a Drama for "The Handmaid's Tale": 2 wds. |
| 40% | ALLISONJANNEY | 13 | "Mom" actress nominated for 2017's Outstanding Lead Actress in a Comedy Series Emmy (2 wds.) |