| 100% | MEANGIRLS | 9 | 2004 comedy film starring Lindsay Lohan and 47-Across (2 wds.) |
| 56% | MEANGIRLS | 9 | 2004 high school comedy starring Lindsay Lohan: 2 wds. |
| 55% | MEANGIRLS | 9 | 2004 high-school comedy starring Lindsay Lohan: 2 wds. |
| 52% | GAMENIGHT | 9 | 2018 action film starring Jason Bateman and 47-Across (2 wds.) |
| 52% | DOCTORSTRANGE | 13 | 2016 superhero film starring Benedict Cumberbatch and 47-Across (2 wds.) |
| 52% | KNOCKEDUP | 9 | Comedy starring Seth Rogen and 47-Across (2 wds.) |
| 51% | MRMOM | 5 | 1983 comedy film starring Michael Keaton and Teri Garr: 2 wds. |
| 51% | NIGHTSCHOOL | 11 | 2018 comedy film starring Tiffany Haddish and Kevin Hart: 2 wds. |
| 50% | NIGHTSCHOOL | 11 | Comedy film starring 15-Across and 45-Across as dropouts working toward a GED (2 wds.) |
| 50% | TROPICTHUNDER | 13 | Action comedy film starring Ben Stiller, Robert Downey Jr. and Jack Black: 2 wds. |
| 49% | MEAN | 4 | "___ Girls," 2004 teen comedy film starring Lindsay Lohan |
| 49% | MIDNIGHTRUN | 11 | 1988 buddy comedy film starring 18-Across, 28-Across, and Robert De Niro (2 wds.) |
| 48% | EASYA | 5 | 2010 teen comedy film starring Emma Stone and Amanda Bynes: 2 wds. |
| 48% | GETSHORTY | 9 | 1995 comedy film starring 17-Across and 30-Across based on an Elmore Leonard novel (2 wds.) |
| 46% | ELLAENCHANTED | 13 | Fantasy comedy film starring Hugh Dancy and 44-Across as characters based on a fairy tale (2 wds.) |
| 46% | MEANGIRLS | 9 | 2004 Lindsay Lohan comedy referenced in Ariana Grande's "thank u, next" music video: 2 wds. |
| 46% | FRIENDSWITH | 11 | "___ Benefits," 2011 romantic comedy film that starred Justin Timberlake and Mila Kunis in the lead roles: 2 wds. |
| 46% | MEANGIRLS | 9 | 2004 Lindsay Lohan movie based partly on the nonfiction book "Queen Bees and Wannabes": 2 wds. |
| 45% | BLUESBROTHERS | 13 | With "The," 1980 musical comedy film starring 18-Across as "Joliet Jake": 2 wds. |
| 45% | OHGOD | 5 | 1977 film comedy starring John Denver and George Burns: 2 wds. |
| 45% | MYFRIENDIRMA | 12 | 1949 comedy film starring 17-Across and 39-Across together for the first time (3 wds.) |
| 44% | THEA | 4 | "___-team," action comedy film starring Liam Neeson and Bradley Cooper: 2 wds. |
| 44% | EASYA | 5 | Teen comedy film starring Emma Stone: 2 wds. |
| 44% | THEPARENTTRAP | 13 | Disney film starring Lindsay Lohan as twin sisters separated at birth (3 wds.) |
| 44% | EASYA | 5 | "___", a teen comedy film starring Emma Stone: 2 wds. |
| 44% | HORRIBLEBOSSES | 14 | 2011 black comedy film starring Jennifer Aniston: 2 wds. |
| 44% | AMERICANPIE | 11 | 1999 raunchy comedy film starring Eugene Levy: 2 wds. |
| 44% | MISTERROBERTS | 13 | 1955 naval comedy film starring James Cagney: 2 wds. |
| 43% | GOTMAIL | 7 | "You've ___," 1998 romantic comedy film starring Tom Hanks and Meg Ryan: 2 wds. |
| 43% | THEGRADUATE | 11 | 1967 romantic comedy film starring Dustin Hoffman and Anne Bancroft based on a Charles Webb novel of the same name: 2 wds. |