| 100% | MEANGIRLS | 9 | 2024 musical teen comedy written by Tina Fey starring 17-Across and 30-Across (2 wds.) |
| 44% | WHENHARRY | 9 | "___ Met Sally...," 1989 romantic comedy film written by Nora Ephron starring Meg Ryan and Billy Crystal: 2 wds. |
| 43% | DATENIGHT | 9 | 2010 comedy starring Steve Carell and Tina Fey: 2 wds. |
| 42% | GETSHORTY | 9 | 1995 comedy film starring 17-Across and 30-Across based on an Elmore Leonard novel (2 wds.) |
| 40% | MARYPOPPINS | 11 | 1964 film starring 17-Across and 30-Across based on children's books by P.L. Travers about a magical nanny (2 wds.) |
| 40% | THEMISFITS | 10 | 1961 John Huston film written by Arthur Miller starring 18-Across and 32-Across (2 wds.) |
| 39% | AMYSCHUMER | 10 | Sketch comedy performer who wrote and stars in 41-Across: 2 wds. |
| 37% | CAFESOCIETY | 11 | A 2016 comedy by Woody Allen starring Steve Carell and Blake Lively: 2 wds |
| 37% | MONSTERSINC | 11 | Pixar film starring 17-Across and 30-Across adapted as a Disney+ series (2 wds.) |
| 37% | COPOUT | 6 | 2010 action comedy directed by Kevin Smith, starring Bruce Willis and Tracy Morgan: 2 wds. |
| 36% | BOUNTYHUNTER | 12 | "The ___," 2010 action comedy film directed by Andy Tennant starring Jennifer Aniston and Gerard Butler: 2 wds. |
| 36% | RABBITTEST | 10 | 1978 film written and directed by 18-Across, starring Billy Crystal as the first pregnant man: 2 wds. |
| 36% | CHASINGAMY | 10 | 1997 romantic comedy directed by Kevin Smith, starring Ben Affleck and Joey Lauren Adams: 2 wds. |
| 36% | BRUCEALMIGHTY | 13 | 2003 fantasy comedy film directed by Tom Shadyac, starring Jennifer Aniston and Jim Carrey: 2 wds. |
| 36% | ROCK | 4 | "30 ___," satirical sitcom about the behind the scenes of a live sketch comedy show created by and starring Tina Fey |
| 36% | KARENBLIXEN | 11 | Danish author who wrote 17-Across and 30-Across under the pen name Isak Dinesen (2 wds.) |
| 36% | MEANGIRLS | 9 | 2004 comedy written by Tina Fey |
| 35% | THEINTERNSHIP | 13 | Comedy set at Google that stars 39-Across and Owen Wilson: 2 wds. |
| 35% | EASYA | 5 | 2010 teen comedy starring Emma Stone and Stanley Tucci: 2 wds. |
| 35% | SWEENEYTODD | 11 | 2007 musical horror film directed by Tim Burton and starring Johnny Depp, for short: 2 wds. |
| 35% | EASYA | 5 | A 2010 teen comedy starring Emma Stone and Stanley Tucci: 2 wds. |
| 35% | EASYA | 5 | 2010 teen comedy film starring Emma Stone and Amanda Bynes: 2 wds. |
| 35% | HARDMILES | 9 | 2024 film starring 15-Across and 30-Across about a difficult bicycle ride from Denver to the Grand Canyon (2 wds.) |
| 35% | BEFORETRILOGY | 13 | Series of three romantic dramas written/directed by Richard Linklater and starring 18-Across and 44-Across (2 wds.) |
| 35% | LIBERALARTS | 11 | 2012 comedy-drama film directed by Josh Radnor and starring Zac Efron and Elizabeth Olsen: 2 wds. |
| 35% | SATURDAYNIGHT | 13 | With 25-Across, NBC sketch comedy series since 1975 whose regulars have included Gilda Radner, Eddie Murphy, and Tina Fey: 2 wds. |
| 35% | LOVELIES | 8 | 2018 hit by 17-Across and Normani: 2 wds. |
| 34% | MONSTERSINC | 11 | 2001 animated comedy starring John Goodman and Billy Crystal with music by 33-Across (2 wds.) |
| 34% | PREFERBLONDES | 13 | "Gentlemen ___," 1953 musical comedy film starring Marilyn Monroe, directed by Howard Hawks: 2 wds. |
| 34% | FOURBROTHERS | 12 | 2005 film starring Mark Wahlberg and Tyrese Gibson directed by 30-Across (2 wds.) |