| 100% | SHELDONCOOPER | 13 | Actor Jim Parsons' most well-known role in the hit television sitcom "The Big Bang Theory": 2 wds. |
| 47% | GALECKI | 7 | Johnny —, actor who plays Leonard Hofstadter in US television sitcom The Big Bang Theory |
| 47% | COOPER | 6 | Sheldon ___, popular television character played by Jim Parsons in the sitcom "The Big Bang Theory" |
| 44% | JIMPARSONS | 10 | "The Big Bang Theory" actor who played Michael in "The Boys in the Band": 2 wds. |
| 42% | JIMPARSONS | 10 | Actor who portrayed Sheldon Cooper in "The Big Bang Theory," and is the narrator in "Young Sheldon": 2 wds. |
| 41% | PARSONS | 7 | Television's Jim ___, known for playing Sheldon in "The Big Bang Theory" |
| 41% | GALECKI | 7 | Johnny —, actor who plays Leonard in US sitcom The Big Bang Theory |
| 41% | GALECKI | 7 | Johnny —, actor who played Leonard in US sitcom The Big Bang Theory |
| 40% | SHELDONCOOPER | 13 | Geeky character played by Jim Parsons on "The Big Bang Theory": 2 wds. |
| 39% | ADAMWEST | 8 | Batman actor from the 1960s who did a guest appearance on "The Big Bang Theory": 2 wds. |
| 38% | RICHARDCROSBY | 13 | Character portrayed by actor Gary Oldman in the hit sitcom "Friends": 2 wds. |
| 38% | SHELDON | 7 | "The Big Bang Theory" role for Jim Parsons |
| 38% | PARSONS | 7 | Jim ___, actor who won the Emmy for Outstanding Lead Actor in a Comedy for "The Big Bang Theory" |
| 38% | EDDIEMURPHY | 11 | "Coming 2 America" actor who played seven roles in the 1996 hit film "The Nutty Professor": 2 wds. |
| 38% | WHITEYWINN | 10 | Character played by actor Thomas Brodie-Sangster in the hit Netflix television drama mini-series "Godless": 2 wds. |
| 37% | ROWANATKINSON | 13 | Actor who voiced Zazu, a hornbill in "The Lion King" and is best known for his role as Mr. Bean: 2 wds. |
| 37% | MAYIM | 5 | ___ Bialik, Emmy-nominated actress best known for her role in "The Big Bang Theory" who has a degree in Neuroscience |
| 37% | WILWHEATON | 10 | "Star Trek: The Next Generation" actor who guest stars as himself on "The Big Bang Theory" (2 wds.) |
| 36% | ARMITAGE | 8 | Child actor Iain who plays the title role in "The Big Bang Theory" spin-off "Young Sheldon" |
| 36% | MARKRUFFALO | 11 | "I Know This Much Is True" actor who won the 2020 Golden Globe Award for Best Actor - Television Motion Picture (2 wds.) |
| 36% | JIMPARSONS | 10 | Actor who plays Sheldon on "The Big Bang Theory" (2 wds.) |
| 36% | JOHNNYGALECKI | 13 | Actor who plays Leonard on "The Big Bang Theory" (2 wds.) |
| 36% | SEANCONNERY | 11 | Scottish actor best known for his role as James Bond, who was knighted in 2000: 2 wds. |
| 36% | MAYIMBIALIK | 11 | "The Big Bang Theory" actress who earned a doctorate in neuroscience from 33-Down: 2 wds. |
| 35% | BRENDANFRASER | 13 | 2023 Best Actor Oscar winner for his role in "The Whale": 2 wds. |
| 35% | ADRIENBRODY | 11 | Actor whose role in 2024's "The Brutalist" is the longest Best Actor-winning performance (screen time 2:08:30): 2 wds. |
| 34% | MAHERSHALAALI | 13 | Actor whose role in 2018's "Green Book" is the longest Best Supporting Actor-winning performance (screen time 1:06:38): 2 wds. |
| 34% | JIMPARSONS | 10 | "The Big Bang Theory" actor who narrates 44-Across (2 wds.) |
| 34% | SHELDONCOOPER | 13 | "The Big Bang Theory" character with the catchphrase "Bazinga!": 2 wds. |
| 34% | MARTINFREEMAN | 13 | Actor whose first big role was Tim Canterbury in the British version of "The Office" (2 wds.) |