| 100% | JOHNNYGALECKI | 13 | Actor who plays Leonard on "The Big Bang Theory" (2 wds.) |
| 87% | JIMPARSONS | 10 | Actor who plays Sheldon on "The Big Bang Theory" (2 wds.) |
| 76% | JIMPARSONS | 10 | "The Big Bang Theory" actor who played Michael in "The Boys in the Band": 2 wds. |
| 75% | KALEYCUOCO | 10 | Actress who plays Penny on "The Big Bang Theory" (2 wds.) |
| 70% | KUNALNAYYAR | 11 | Actor who played Raj on “The Big Bang Theory” |
| 70% | GALECKI | 7 | Johnny —, actor who plays Leonard in US sitcom The Big Bang Theory |
| 70% | GALECKI | 7 | Johnny —, actor who played Leonard in US sitcom The Big Bang Theory |
| 69% | GALECKI | 7 | Johnny —, actor who plays Leonard Hofstadter in US television sitcom The Big Bang Theory |
| 67% | ADAMWEST | 8 | Batman actor from the 1960s who did a guest appearance on "The Big Bang Theory": 2 wds. |
| 66% | JUDDHIRSCH | 10 | "Superior Donuts" actor who guest stars as Leonard's dad on "The Big Bang Theory" (2 wds.) |
| 66% | PARSONS | 7 | Jim who plays Sheldon on The Big Bang Theory |
| 66% | WIL | 3 | Wheaton who plays himself on The Big Bang Theory |
| 62% | JIMPARSONS | 10 | "The Big Bang Theory" actor who narrates 44-Across (2 wds.) |
| 62% | LAURIEMETCALF | 13 | "The Conners" actress who played Sheldon's mother on "The Big Bang Theory" (2 wds.) |
| 61% | ALEXKARRAS | 10 | Actor who played the adoptive father on "Webster": 2 wds. |
| 61% | EMMANUELLEWIS | 13 | Actor who played the title character on "Webster": 2 wds. |
| 61% | JOSHUAJACKSON | 13 | Actor who played Pacey on the 1998-2003 teen drama "Dawson's Creek": 2 wds. |
| 61% | BOYDHOLBROOK | 12 | "Logan" actor who plays the Corinthian on "The Sandman": 2 wds. |
| 60% | SHELDONCOOPER | 13 | Geeky character played by Jim Parsons on "The Big Bang Theory": 2 wds. |
| 60% | SEANGIAMBRONE | 13 | Actor who plays the geeky boy, Adam, on 18-Across: 2 wds. |
| 60% | VICTAYBACK | 10 | Actor who played diner owner Mel on the sitcom "Alice": 2 wds. |
| 60% | WILWHEATON | 10 | "Star Trek: The Next Generation" actor who guest stars as himself on "The Big Bang Theory" (2 wds.) |
| 60% | WIL | 3 | Wheaton who played himself on "The Big Bang Theory" |
| 60% | CUOCO | 5 | Kaley who played Penny on "The Big Bang Theory" |
| 60% | DANNYBONADUCE | 13 | Actor who played the wisecracking middle child on "The Partridge Family": 2 wds. |
| 60% | SETHGREEN | 9 | Actor who played Daniel "Oz" Osbourne on "Buffy the Vampire Slayer": 2 wds. |
| 60% | FRANKIEMUNIZ | 12 | Actor who played child prodigy Malcolm on "Malcolm in the Middle": 2 wds. |
| 60% | KATEYSAGAL | 10 | "Sons of Anarchy" actress who played Penny's mother on "The Big Bang Theory" (2 wds.) |
| 59% | SPENCERTRACY | 12 | Actor who played the lawyer based on Clarence Darrow in 32-Across: 2 wds. |
| 59% | RANDALLPARK | 11 | Actor who plays Louis, the dad on "Fresh Off the Boat": 2 wds. |