| 100% | MARGOTROBBIE | 12 | Actress who played 14-Across, 26-Across, and Queen Elizabeth I in "Mary Queen of Scots" (2 wds.) |
| 71% | MARGOTROBBIE | 12 | "I, Tonya" actress who plays Queen Elizabeth I in "Mary Queen of Scots": 2 wds. |
| 68% | MARGOTROBBIE | 12 | "I, Tonya" actress who plays Queen Elizabeth I in "Mary Queen of Scots" (2 wds.) |
| 60% | SAOIRSERONAN | 12 | "Lady Bird" actress who plays Mary Stuart in "Mary Queen of Scots": 2 wds. |
| 59% | MIAWASIKOWSKA | 13 | Actress who played the daughter of 14- and 32-Across in "The Kids Are All Right": 2 wds. |
| 57% | SAOIRSERONAN | 12 | "Lady Bird" actress who plays Mary Stuart in "Mary Queen of Scots" (2 wds.) |
| 57% | CATE | 4 | ___ Blanchett, actress who earned 2 Oscar nominations for playing Queen Elizabeth I, in "Elizabeth" and its sequel |
| 55% | CATEBLANCHETT | 13 | Actress who played Queen Elizabeth I in the 1998 movie "Elizabeth": 2 wds. |
| 55% | CATEBLANCHETT | 13 | Australian actress who played Queen Elizabeth I in 1998's "Elizabeth": 2 wds. |
| 55% | GEMMACHAN | 9 | "Crazy Rich Asians" actress who plays Bess of Hardwick in "Mary Queen of Scots" (2 wds.) |
| 53% | CATEBLANCHETT | 13 | Actress who plays Queen Elizabeth I in "Elizabeth" (2 wds.) |
| 53% | SAOIRSERONAN | 12 | "Brooklyn" actress who portrayed Queen Mary in "Mary Queen of Scots": 2 wds. |
| 52% | CLAIREFOY | 9 | Actress who played Queen Elizabeth II in the historical drama TV series "The Crown" and also starred in "Crossbones" as Kate Balfour: 2 wds. |
| 51% | OLIVIACOLMAN | 12 | "Broadchurch" actress who plays Queen Elizabeth in season 3 of "The Crown" (2 wds.) |
| 51% | ANDIEMACDOWELL | 14 | "Sex, Lies, and Videotape" actress who played producer Rita Hanson in 14-Across: 2 wds. |
| 50% | OLIVIACOLMAN | 12 | Actress who played Queen Elizabeth II on two seasons of Netflix's "The Crown": 2 wds. |
| 50% | DAVIDTENNANT | 12 | "Doctor Who" actor who plays John Knox in "Mary Queen of Scots": 2 wds. |
| 49% | JUDIDENCH | 9 | Actress who plays Queen Victoria in "Mrs Brown" and "Victoria & Abdul" (2 wds.) |
| 49% | ANGELABASSETT | 13 | Actress who plays the queen mother of Wakanda in "Black Panther": 2 wds. |
| 49% | EMMATHOMPSON | 12 | "The Remains of the Day" actress who played Elinor Dashwood in "Sense and Sensibility": 2 wds. |
| 49% | WHITNEYHOUSTON | 14 | Singer and actress who played Rachel Marron in 18a and whose cover of "I Will Always Love You" became a best-selling single: 2 wds. |
| 49% | EVALONGORIA | 11 | "Overboard" actress who plays Dora's mother in "Dora and the Lost City of Gold": 2 wds. |
| 48% | TESSATHOMPSON | 13 | "Creed II" actress who plays Valkyrie, the ruler of New Asgard, in "Thor: Love and Thunder": 2 wds. |
| 48% | HELENMIRREN | 11 | Actress who won a Best Actress Oscar as Queen Elizabeth II in "The Queen": 2 wds. |
| 48% | MOLLYRINGWALD | 13 | Actress who played Sam Baker in the 1984 film "Sixteen Candles" and Mary Andrews on "Riverdale" in 2019: 2 wds. |
| 48% | KATIELEUNG | 10 | "Harry Potter and the Goblet of Fire" actress who plays Fan in "The Foreigner": 2 wds. |
| 47% | JENNIFERLEE | 11 | Actress who voiced Queen of Arendelle, Anna and Elsa's mother in the musical fantasy film, "Frozen": 2 wds. |
| 47% | JULIEANDREWS | 12 | "The Sound of Music" actress who played the nanny Mary Poppins in the 1964 film: 2 wds. |
| 47% | ANYATAYLORJOY | 13 | "The Queen's Gambit" actress who plays Olga of the Birch Forest in 39-Across (2 wds.) |
| 47% | ISABELAMERCED | 13 | "Dora and the Lost City of Gold" actress who plays Anya Corazon in "Madame Web": 2 wds. |