| 100% | WINONARYDER | 11 | Actress who plays a grandmother who tells the story of why it always snows on Christmas in Lutz, Florida, in "Edward Scissorhands" (2 wds.) |
| 37% | NANCYTRAVIS | 11 | "The Kominsky Method" actress who plays the grandmother of a critically ill girl in the 2024 film "Ordinary Angels" (2 wds.) |
| 37% | ZOESALDANA | 10 | "Avatar" actress who played a pirate in the first "Pirates of the Caribbean" film: 2 wds. |
| 37% | WHOOPIGOLDBERG | 14 | "Sister Act" actress who played God in the films "A Little Bit of Heaven" and "It's a Very Merry Muppet Christmas Movie" (2 wds.) |
| 37% | MARLEEMATLIN | 12 | "CODA" actress who played a deaf employee at the school in "Children of a Lesser God": 2 wds. |
| 37% | JULIANNEMOORE | 13 | Actress who plays an activist aiding a pregnant woman in a dystopian retelling of the nativity story in "Children of Men" (2 wds.) |
| 36% | INGRIDBERGMAN | 13 | "Casablanca" actress who played a Swedish missionary in "Murder on the Orient Express": 2 wds. |
| 36% | BRIELARSON | 10 | Actress who plays the character of Carol Danvers, a former U.S. Air Force pilot in "Captain Marvel": 2 wds. |
| 36% | DIANEKEATON | 11 | Actress who plays a mother in "Father of the Bride" (2 wds.) |
| 35% | SUSANSARANDON | 13 | Actress who played Louise, one of the title characters on the run in 1991's "Thelma & Louise": 2 wds. |
| 35% | KIRSTENDUNST | 12 | "The Power of the Dog" actress who plays a journalist in the new movie "Civil War": 2 wds. |
| 35% | SUTTONFOSTER | 12 | "Younger" actress who played Princess Winnifred in the 2024 Broadway revival of "Once Upon a Mattress": 2 wds. |
| 35% | FELICITYJONES | 13 | Actress who played Ruth Bader Ginsburg in the film "On the Basis of Sex": 2 wds. |
| 35% | UZOADUBA | 8 | "In Treatment" actress who plays a detective on the Netflix series "The Residence": 2 wds. |
| 35% | AMYPOEHLER | 10 | Actress who played the role of Leslie Knope in "Parks and Recreation", a role she is best-known for: 2 wds. |
| 34% | RACHELMCADAMS | 13 | "Spotlight" actress who plays a surgeon in "Doctor Strange in the Multiverse of Madness" (2 wds.) |
| 34% | MERYLSTREEP | 11 | "The Devil Wears Prada" actress who plays a struggling actress on "Only Murders in the Building" (2 wds.) |
| 34% | TRACEYULLMAN | 12 | "Into the Woods" actress who played Princess Winnifred in the 2005 made-for-TV version of "Once Upon a Mattress": 2 wds. |
| 34% | WINONARYDER | 11 | "Edward Scissorhands" actress, who plays a lead role in "Stranger Things": 2 wds. |
| 34% | SARAHPAULSON | 12 | "American Horror Story" actress who won the 2024 Best Leading Actress in a Play Tony for "Appropriate": 2 wds. |
| 33% | KARYNPARSONS | 12 | Actress who played the snobbish cousin of 17-Across in "The Fresh Prince of Bel-Air," which is rumored to be getting a reunion: 2 wds. |
| 33% | XOCHITLGOMEZ | 12 | "The Baby-Sitters Club" actress who plays a time-traveling teenager in "Doctor Strange in the Multiverse of Madness" (2 wds.) |
| 33% | SELENAGOMEZ | 11 | "Wizards of Waverly Place" actress who plays Mabel on "Only Murders in the Building" (2 wds.) |
| 33% | HOPEDAVIS | 9 | "Wayward Pines" actress who plays the wife of a mob boss on 54-Across (2 wds.) |
| 33% | WHITNEYHOUSTON | 14 | Singer and actress who played Rachel Marron in 18a and whose cover of "I Will Always Love You" became a best-selling single: 2 wds. |
| 33% | LEAHLEWIS | 9 | "The Half of It" actress who plays Georgia "George" Fan on "Nancy Drew": 2 wds. |
| 33% | GINARODRIGUEZ | 13 | "Jane the Virgin" actress who plays the future President of the United States on "Diary of a Future President" (2 wds.) |
| 33% | HUNTERSCHAFER | 13 | "Euphoria" actress who plays Tigris Snow in "The Hunger Games: The Ballad of Songbirds & Snakes" (2 wds.) |
| 33% | NICOLEKIDMAN | 12 | "Big Little Lies" actress who plays Julia Edwards on "Top of the Lake: China Girl" (2 wds.) |
| 33% | SARAHPAULSON | 12 | "American Horror Story" actress who plays the title character, 46-Across, on a Netflix miniseries (2 wds.) |