| 100% | SHREK | 5 | Animated character who was Donkey's friend |
| 56% | GENIE | 5 | Animated character who sings Friend Like Me |
| 54% | SAM | 3 | Tolkien character who is a friend to Frodo |
| 52% | GEORGECOSTANZA | 14 | Character who is Jerry's best friend since high school and is played by Jason Alexander on the show "Seinfeld": 2 wds. |
| 51% | SHREK | 5 | Character who explains to Donkey that ogres are like onions |
| 50% | SHREK | 5 | Layered Scottish ogre who is friends with Donkey |
| 50% | HELLOKITTY | 10 | Animated character who's five apples tall |
| 49% | DORATHEEXPLORER | 15 | Animated TV character whose best friend is Boots |
| 49% | DIDDY | 5 | ___ Kong, monkey character who is a sidekick to Donkey Kong in the video game franchise |
| 48% | ROSS | 4 | "Friends" character who is a paleontologist |
| 47% | SYLVESTER | 9 | Animated character who's the subject of this puzzle's theme |
| 47% | MIKEWHEELER | 11 | Played by Finn Wolfhard, character who is one of Will Byers' three friends in "Stranger Things": 2 wds. |
| 46% | LOIS | 4 | Comic strip title character who is Beetle Bailey's sister |
| 46% | OLAF | 4 | Animated snowman who's Anna's friend |
| 45% | KIFF | 4 | Animated musical TV series featuring a rabbit character, Barry Buns, who is the titular character's best friend |
| 45% | GUS | 3 | Mouse who was best friends with the protagonist in the 1950 animated musical fantasy film "Cinderella" |
| 45% | HUCKLEBERRY | 11 | ___ Finn, a fictional character who first appeared in 51a and is a friend of the protagonist |
| 45% | HOMER | 5 | TV character who said "I am so smart! I am so smart! S-M-R-T!" |
| 45% | QUASIMODO | 9 | Character who is decidedly ungainly |
| 44% | DOC | 3 | Bespectacled dwarf who was Snow White's friend |
| 44% | ODIE | 4 | Comics character who's asked, "Is it true you became man's best friend by bribing somebody?" |
| 44% | DOUG | 4 | Nickelodeon title character who's friends with Skeeter |
| 44% | SHARK | 5 | "___ Tale," 2004 animated comedy movie starring Will Smith who voices a "fish" character |
| 44% | DAISY | 5 | ___ Duck, cartoon bird character who is Donald Duck's girlfriend from "Quack Pack" |
| 44% | KRUSTY | 6 | With 21-Across, "The Simpsons" character who is a children's TV host |
| 44% | EZRA | 4 | Pound who was a friend of T.S. Eliot |
| 44% | YOGI | 4 | ___ Bear (cartoon character who's friends with Boo-Boo) |
| 44% | ELSA | 4 | Animated character who sings "Let It Go" |
| 44% | GROMIT | 6 | Animated character who graduated from Dogwarts University |
| 44% | WALLE | 5 | Animated character who likes "Hello, Dolly!" songs |