| 100% | STARGATE | 8 | Atlantis, Universe, SG-1 series |
| 36% | SURVIVE | 7 | Netflix series, Formula 1: Drive to __ |
| 36% | WANDAVISION | 11 | Disney+ series in the Marvel Cinematic Universe |
| 34% | ANDOR | 5 | Disney+ series set in the "Star Wars" universe |
| 34% | DOOM | 4 | "___ Patrol" (DC Universe web series starring Brendan Fraser) |
| 33% | AMYMANSON | 9 | Scottish actress who played Medea in 2010s BBC series Atlantis |
| 32% | DOOM | 4 | "___ Patrol" (DC Universe series starring Brendan Fraser and Alan Tudyk) |
| 32% | LPS | 3 | They’re profiled in the 33 1/3 book series |
| 31% | HEMAN | 5 | "___ and the Masters of the Universe," popular animated cartoon series: Hyph. |
| 30% | CONANOBRIEN | 11 | Fifth in a series of five TV personalities (starting June 1, 2009) |
| 29% | FIBONACCI | 9 | Eponym of a number series that begins 1, 1, 2, 3, 5, 8, ... |
| 29% | ETS | 3 | Some "Stargate SG-1" characters, in brief |
| 28% | FIRECOUNTRY | 11 | 1-Down drama series starring 19-Across and 34-Across set in Northern California (2 wds.) |
| 28% | LOVE | 4 | "___ Is 1-Down," Netflix series whose contestants get engaged without ever seeing each other |
| 27% | MARVEL | 6 | The ___ Cinematic Universe (series of films) |
| 27% | MAN | 3 | "He-___ and the Masters of the Universe," animated series that ran from 1983 to 1985 |
| 27% | LADIES | 6 | "The No. 1 ___ Detective Agency" (first novel in a mystery series by Alexander McCall Smith) |
| 26% | LONE | 4 | "9-1-1: ___ Star" (Rob Lowe series) |
| 26% | DALLASKEUCHEL | 13 | Astros starting pitcher who won Game 1 of the 2017 American League Championship Series (2 wds.) |
| 26% | LETAFOOL | 8 | Part 1 of a maxim by Publilius Syrus, hinted at by the series of circled letters |
| 26% | DRIVETO | 7 | With 37-Across, subtitle of a hit Netflix documentary series about Formula 1 racing (2 wds.) |
| 26% | FIREFLY | 7 | Critically acclaimed 2002 sci-fi drama series starring Nathan Fillion that was canceled after 1 season |
| 25% | MACROCOSM | 9 | Universe |
| 25% | REALM | 5 | Universe |
| 25% | SPACE | 5 | Universe |
| 25% | COSMOS | 6 | Universe |
| 25% | WORLD | 5 | Universe |
| 25% | RUN | 3 | Series |
| 25% | TVSHOW | 6 | Series |
| 25% | STRING | 6 | Series |