| 100% | ARF | 3 | Call from one's best friend? |
| 56% | SPAM | 4 | Many a phone call from one's own area code, nowadays |
| 56% | DOG | 3 | "Man's best friend"; Snoopy was one |
| 56% | WHOSAGOODBOY | 12 | Question to one's best friend, maybe |
| 55% | PEER | 4 | ___ pressure (pressure from one's friends to conform) |
| 54% | MOIRA | 5 | Offred's best friend from "The Handmaid's Tale" |
| 54% | PEER | 4 | Kind of pressure from one's circle of friends? |
| 53% | RAISE | 5 | Good news from one's employer |
| 51% | IFOLD | 5 | Remark from one who's obviously not going to call |
| 50% | TERESA | 6 | One of Barbie's best friends |
| 48% | ELMO | 4 | One of Zoe's best friends on "Sesame Street" |
| 47% | UMP | 3 | One calling from home? |
| 47% | UMP | 3 | One calling from home |
| 47% | ENABLER | 7 | One who's a well-meaning but bad influence on a friend, maybe |
| 46% | JANE | 4 | She is a strong and intelligent character from one of Charlotte Bronte's best known classics |
| 46% | AESIR | 5 | One of Odin's best buddies, from the viewpoint of old Norsemen |
| 46% | PENPAL | 6 | What a best friend from camp might become |
| 46% | DOG | 3 | Animal sometimes called "man's best friend" |
| 46% | IMOUT | 5 | Words from one who'd rather not call? |
| 45% | MIDGE | 5 | Barbie the doll's best friend |
| 45% | YODELER | 7 | One calling from a Swiss mountaintop |
| 45% | DOG | 3 | Jake the ___, Finn's best friend from the animated series "Adventure Time," who is associated with the color at 42a |
| 45% | EERIE | 5 | Like a call from someone one just thought about |
| 45% | USER | 4 | One who's not a good friend |
| 44% | UMPIRE | 6 | One making calls from home |
| 44% | UMP | 3 | One making calls from home |
| 44% | NATAL | 5 | From one's earliest days |
| 44% | ARE | 3 | "Diamonds ___ a girl's best friend" |
| 44% | RON | 3 | ___ Weasley (Harry Potter's best friend) |
| 44% | RON | 3 | Weasley, Harry Potter's best friend |