| 100% | BETSY | 5 | Creator of the first American Flag, first name |
| 83% | BETSYROSS | 9 | Legendary creator of the first American flag |
| 66% | ASTOR | 5 | Family name of the first American multimillionaire |
| 63% | ADA | 3 | Coding language named after the creator of the first computer program |
| 57% | ARTHURWYNNE | 11 | Creator of the first crossword |
| 56% | ERLE | 4 | First name of the best-selling American author of the 20th century (as of 1970) |
| 56% | RCA | 3 | Creator of the first radio network |
| 55% | STAN | 4 | First name of the dad on "American Dad!" |
| 55% | ATHENA | 6 | Mythical creator of the first spider |
| 54% | ELSA | 4 | Woman's name that's also the first four letters of a Central American country name |
| 54% | REDANDWHITE | 11 | Like the Canadian flag ... and a hint to the first names of 24- and 48-Across |
| 53% | ARLINGTON | 9 | Site of the first Six Flags theme park |
| 53% | INITIAL | 7 | The first letter of your name |
| 53% | DOLLY | 5 | Name of the first cloned sheep |
| 53% | LAIKA | 5 | Name of the first dog in space |
| 52% | BETSY | 5 | Ross who is credited with creating the first American flag |
| 52% | ERIK | 4 | The Phantom of the Opera's first name |
| 52% | ALAN | 4 | Former head of the Federal Reserve, first name |
| 52% | COLUMBIA | 8 | Name of the first space shuttle, launched 1981 |
| 51% | STANTON | 7 | First president of the National American Woman Suffrage Association |
| 51% | EDWINA | 6 | Given name of the first Countess Mountbatten |
| 51% | ISSA | 4 | First name of both a co-creator of Insecure and the character she plays |
| 50% | GLINDA | 6 | Good Witch of the South's first name |
| 50% | STEPHEN | 7 | English name of the first king of Hungary |
| 50% | MICHELLE | 8 | First name of the First Lady |
| 50% | ABRAM | 5 | First name of the first patriarch |
| 50% | BEN | 3 | First name of the newest Batman |
| 50% | PABLO | 5 | First name of the artist Picasso |
| 50% | ANTON | 5 | First name of Chekhov, the playwright |
| 50% | ARIEL | 5 | First name of the Little Mermaid |