| 100% | LETTERMAN | 9 | David __, US TV talk show host for 33 years |
| 46% | JIMMYKIMMEL | 11 | Talk show host who recently hosted the Oscars for the second year in a row: 2 wds. |
| 45% | ALLEN | 5 | TV talk show host of yore |
| 45% | SURVIVOR | 8 | TV show hosted in US by Jeff Probst for 40 seasons |
| 44% | IRV | 3 | Old TV talk show host Kupcinet |
| 44% | RIPA | 4 | Morning TV talk show host Kelly |
| 44% | TAVIS | 5 | Former TV talk show host Smiley |
| 44% | LETTERMAN | 9 | Talk show host David ___ |
| 42% | LETTERMAN | 9 | Former talk show host david |
| 42% | OPRAH | 5 | Talk show host nominated for an Academy Award |
| 41% | JERRYSPRINGER | 13 | TV talk show host with a law degree from Northwestern University: 2 wds. |
| 41% | ELLEN | 5 | Talk show host known for dancing in the audience |
| 40% | OPRAHWINFREY | 12 | TV talk show host who received the NAACP's Spingarn Medal in 2000: 2 wds. |
| 39% | ELLEN | 5 | Longtime talk show host known for pulling pranks on her guests |
| 38% | CHANDLERBING | 12 | Cherry for talk show host Chelsea? |
| 37% | COCO | 4 | Nickname for talk show host O'Brien |
| 37% | MARIEOSMOND | 11 | Singer and talk show host who has been a spokesperson for Nutrisystem: 2 wds. |
| 37% | WINFREY | 7 | Oprah __, US talk show host |
| 36% | XXXX | 4 | "The Tonight Show" host for five years |
| 36% | PYNE | 4 | 60's TV talk-show host Joe |
| 36% | LATENITE | 8 | Time for many TV talk shows, informally |
| 36% | SAJAK | 5 | Game show host Pat who was nominated for two Emmys this year |
| 36% | JOHNNYCARSON | 12 | American talk show host and comedian who hosted "The Tonight Show" for three straight decades: 2 wds. |
| 36% | SATURDAY | 8 | "___ Night Live," American talk show starring David Schwimmer as the host in 1995 |
| 35% | RIVERS | 6 | Former host Joan known for saying, "Can we talk?" |
| 35% | ROSIETHERIVER | 13 | Waterway named for a talk show host? |
| 35% | DESK | 4 | Furniture piece for a talk show host |
| 34% | ELLEN | 5 | Talk show host DeGeneres |
| 34% | PHIL | 4 | Talk show host Dr. ___ |
| 34% | LEEZA | 5 | Talk show host Gibbons |