| 100% | CHRISTIAN | 9 | Film actor Bale, who was the first Non-American to portray Batman/ Bruce Wayne |
| 49% | POITIER | 7 | Sidney who was the first African American to win a Best Actor Oscar |
| 48% | BARRY | 5 | ___ Nelson, American actor who was the first to portray James Bond in a television series titled "Climax!" |
| 45% | POITIER | 7 | Sidney who was the first African-American to win a Best Actor Oscar |
| 44% | NIMOY | 5 | Actor Leonard who was the first to play Spock |
| 43% | WES | 3 | Actor Studi who will be the first Native American actor to receive an honorary Oscar |
| 43% | ALEC | 4 | Actor Guinness who was the first to play Obi-Wan Kenobi |
| 43% | LIN | 3 | Jeremy who was the first Asian American to win an NBA Championship |
| 43% | TOBEY | 5 | Actor Maguire who was the first to play Spider-Man in movies |
| 43% | GLENN | 5 | John who was the first American to orbit the earth |
| 43% | IRA | 3 | Aldridge who was the first Black actor to play Othello |
| 42% | ETHEL | 5 | Waters who was the first Black American to host a national television show |
| 42% | LORRE | 5 | Peter who was the first actor to play a Bond villain |
| 42% | ALI | 3 | Mahershala who was the first Muslim actor to win an Oscar |
| 42% | BUNCHE | 6 | Ralph who was the first African American to be awarded the Nobel Peace Prize |
| 42% | RONDA | 5 | Rousey who was the first American woman to win an Olympic judo medal |
| 41% | JANEADDAMS | 10 | Social worker who was the first American woman to win the Nobel Peace Prize |
| 41% | REBA | 4 | McEntire who is the first woman to portray Colonel Sanders in a KFC ad |
| 41% | VIOLA | 5 | Actress Davis who was the first African American to win the Triple Crown of Acting |
| 41% | SUNILEE | 7 | Gymnast who was the first Hmong American athlete to compete in the Olympics |
| 40% | STEVEN | 6 | Yeun who was the first Asian American nominated for Best Actor (2020's "Minari") |
| 40% | MARIA | 5 | ___ Mitchell, astronomer who was the first female professor of astronomy and the first American to discover a comet |
| 40% | JACOBY | 6 | Ellsbury who was the first Native American of Navajo descent to play in Major League Baseball |
| 39% | SEATTLESLEW | 11 | 1977 Triple Crown winner who was the first American champion to have been undefeated in previous races: 2 wds. |
| 39% | LINDSEY | 7 | ___ Vonn, former alpine ski racer who was the first American woman to win an Olympic gold in downhill skiing |
| 39% | ALYN | 4 | Kirk ___, actor who was the first to play Superman |
| 38% | HATTIE | 6 | Actress McDaniel who was the first African-American to win an Academy Award |
| 38% | SEAN | 4 | Actor Connery who was the first James Bond |
| 38% | DAWES | 5 | American gymnast Dominique who was the first Black athlete to win an Olympic gold medal in gymnastics |
| 38% | DANDRIDGE | 9 | Singer Dorothy who was the first African-American to get a Best Actress Oscar nomination |