| 100% | DISCOVERY | 9 | First shuttle to be retired by NASA |
| 59% | DISCOVERY | 9 | First operational space shuttle to be retired |
| 48% | EROS | 4 | First asteroid to be orbited by a spacecraft (2000) |
| 43% | ENTERPRISE | 10 | NASA's first Space Shuttle orbiter constructed by Rockwell International |
| 43% | BRAD | 4 | First Maverick to have his jersey retired- it was #15- ___ Davis |
| 42% | COLUMBIA | 8 | NASA's first space-rated Space Shuttle orbiter constructed by Rockwell International |
| 41% | ENDEAVOUR | 9 | NASA Space Shuttle aka OV-105 whose first mission was in May, 1992 |
| 41% | ENDEAVOUR | 9 | NASA Space Shuttle aka OV-105 whose first mission was in May 1992 |
| 41% | YMCA | 4 | Org. that is often referred to by just its first letter |
| 41% | GEHRIG | 6 | Yankee who was the first major-leaguer to have his number retired |
| 40% | NEIL | 4 | First name in NASA's prestigious list of astronauts who have been to the moon |
| 40% | CPR | 3 | First-aid procedure that can be done to the beat of "360" by Charlie XCX |
| 40% | NONET | 5 | A chamber work by Louis Spohr was the first to bear this title |
| 39% | STANMUSIAL | 10 | Slugger born November 21, 1920 whose number was the first to be retired by the St. Louis Cardinals (2 wds.) |
| 39% | INCAREOF | 8 | To be handled by |
| 38% | MCGWIRE | 7 | Retired first baseman Mark, who's been conspicuously denied entry to the Baseball Hall of Fame since 2007 |
| 38% | HODGES | 6 | His #14 was retired by the Mets |
| 38% | EPEE | 4 | First weapon to be electrified |
| 38% | EWE | 3 | First mammal to be cloned |
| 38% | HATH | 4 | First verb to be telegraphed |
| 37% | ONE | 3 | It was retired by the Yankees in 1986 |
| 37% | KAREEM | 6 | His number 33 is retired by the Lakers |
| 37% | IVERSON | 7 | Allen whose #3 was retired by the 76ers |
| 37% | POSADA | 6 | Jorge, whose number was retired by the Yankees |
| 37% | OTT | 3 | His number 4 was retired by the Giants |
| 37% | YAO | 3 | Ming whose number was retired by the Rockets |
| 37% | TORRE | 5 | His number 6 was retired by the Yankees |
| 37% | FOR2 | 4 | To be shared by a couple |
| 37% | RABBI | 5 | Osnat Barzani is thought by some to have been the first female one |
| 37% | JOSECANSECO | 11 | Retired ballplayer who was the first to hit 40 homers and steal 40 bases in the same season: 2 wds. |