| 100% | MEIR | 4 | First U.S. citizen to become Israel’s P.M. |
| 51% | BURR | 4 | First U.S. vice president not to become president |
| 49% | TEXAS | 5 | U.S.S. ___, first battleship to become a state shrine |
| 47% | RADIO | 5 | In 1922, Warren G. Harding became the first U.S. president to be broadcast over this |
| 45% | OMAR | 4 | Ilhan ___, who became the first Somali-American elected to the U.S. Congress (November, 2018) |
| 44% | PALMSPRINGS | 11 | California city that, in 2018, became the first U.S. city to have an all-L.G.B.T. city council |
| 43% | BLACKWELL | 9 | Elizabeth __, first woman in US to become a doctor |
| 43% | ADA | 3 | ___ Limon, first Latina to become a US Poet Laureate |
| 43% | VERMONT | 7 | First U.S. state to abolish slavery |
| 43% | NIXON | 5 | First U.S. President to visit China |
| 43% | STLOUIS | 7 | First U.S. city to host the Olympics |
| 43% | GLENN | 5 | First U.S. astronaut to circle the earth |
| 43% | PENNY | 5 | First U.S. coin to feature a president |
| 42% | YANQUI | 6 | U.S. citizen, to Latin Americans |
| 42% | WARRENGHARDING | 14 | U.S. president who, in 1922, became the first president to have his voice transmitted on the radio (3 wds.) |
| 42% | OBERLIN | 7 | First U.S. college to award degrees to women |
| 42% | HST | 3 | First U.S. pres. to travel in a submarine |
| 42% | STLOUIS | 7 | First U.S. city to host the Olympic Games |
| 42% | STL | 3 | First U.S. city to host the Olympics (Abbr.) |
| 42% | YALE | 4 | First U.S. university to award a Ph.D. |
| 42% | STL | 3 | First U.S. city to host the Olympic Games |
| 41% | HAMPSHIRE | 9 | First U.S. college to divest from apartheid South Africa |
| 41% | APPLE | 5 | First U.S. company to be valued at $1 trillion |
| 41% | DETROIT | 7 | First U.S. city to pave a road for cars |
| 41% | EBAN | 4 | Israel's first U.N. delegate |
| 41% | EBAN | 4 | Israel's first U.N. representative |
| 41% | ABBAEBAN | 8 | Israel's first U.N. representative |
| 41% | PENNY | 5 | First U.S. coin to feature a real person’s image |
| 41% | SHIRLEYCHISHOLM | 15 | First Black woman elected to the U.S. Congress |
| 40% | ALLY | 4 | Israel, to the U.S. |