| 100% | BARNEY | 6 | Fred's best friend in the animated sitcom "The Flintstones" |
| 59% | SHIRLEY | 7 | Laverne's best friend in the 1970s sitcom starring Penny Marshall and Cindy Williams |
| 57% | DAVE | 4 | ___ Coulier, who played Joey Gladstone, Jesse and Danny's best friend in the 1987 sitcom "Full House" |
| 57% | ANDREABARBER | 12 | Actress who played Kimmy Gibbler, D.J's best friend in the 1987 sitcom "Full House:" 2 wds. |
| 57% | BOOTS | 5 | Dora's furry monkey best friend in the animated children's TV series, "Dora the Explorer" |
| 56% | CHANDLER | 8 | Joey's best friend in the sitcom "F.R.I.E.N.D.S" |
| 52% | STAR | 4 | Patrick ___, SpongeBob's best friend and neighbor in the animated TV series, "SpongeBob SquarePants" |
| 51% | MILHOUSE | 8 | Bart's best friend in The Simpsons |
| 50% | PAULIE | 6 | Rocky's best friend in the "Rocky" films |
| 49% | FLOUNDER | 8 | Fish, Ariel's best friend in The Little Mermaid |
| 49% | GUS | 3 | Mouse who was best friends with the protagonist in the 1950 animated musical fantasy film "Cinderella" |
| 49% | NED | 3 | Peter Parker's best friend in the "Spider-Man" franchise |
| 49% | EDDIE | 5 | ___ Thomas, Raven's male best friend portrayed by Orlando Brown in the sitcom "That's So Raven" |
| 48% | NED | 3 | Leeds who is Spider-Man's best friend in the MCU movies |
| 48% | CHELSEA | 7 | ___ Daniels, Raven's female best friend portrayed by Anneliese van der Pol in the sitcom "That's So Raven" |
| 48% | RUBBLE | 6 | Fred Flintstone's best friend, Barney |
| 47% | SAMWISE | 7 | Frodo's best friend in Lord of the Rings |
| 47% | TICO | 4 | Dora's squirrel friend in the animated children's TV series, "Dora the Explorer" |
| 47% | CAL | 3 | Ricky's best friend in Talladega Nights: The Ballad of Ricky Bobby |
| 46% | WILMA | 5 | Fred's wife in The Flintstones |
| 45% | LILO | 4 | ___ Pelekai who's Stitch's best friend in a Disney animated franchise |
| 45% | RHODA | 5 | Mary's best friend on the CBS sitcom "The Mary Tyler Moore Show" starring Mary Tyler Moore and Valerie Harper |
| 45% | PINKY | 5 | The Brain's friend in a 1990s animated series |
| 44% | DAISY | 5 | Green diesel railcar in the animated children's TV series, "Thomas & Friends" |
| 44% | NALA | 4 | Simba's best friend in "The Lion King" |
| 44% | MIA | 3 | Lucia's best friend in "The White Lotus" |
| 44% | INN | 3 | The Sodor ___, lodging place that appears in the animated children's TV series, "Thomas & Friends" |
| 44% | MELANIE | 7 | Scarlett's sister-in-law and best friend in "Gone With the Wind" |
| 44% | DOG | 3 | Jake the ___, Finn's best friend from the animated series "Adventure Time," who is associated with the color at 42a |
| 43% | ARLO | 4 | Dinosaur in the animated movie "The Good Dinosaur" |