| 100% | DISEASE | 7 | Heart ___ can lead to heart attacks and runs in families |
| 42% | ANXIETIES | 9 | Worries that can lead to an attack |
| 39% | APPLEOFDISCORD | 14 | WARNING: Improper use could lead to jealousy, treachery and/or war |
| 37% | IVEGOT | 6 | Lead-in to "Five Dollars" and "Sixpence" in song titles |
| 36% | DERMA | 5 | Lead-in to -planing and -brasion, in skin care |
| 35% | SHE | 3 | Lead-in to "Bop" and "Wolf" in hits by Cyndi Lauper and Shakira |
| 35% | NEWT | 4 | Lead role in "Fantastic Beasts and Where to Find Them" |
| 34% | TEETER | 6 | Alien runs back and forth to queen, in a wobble |
| 33% | LEOVII | 6 | Pope said to have died from a heart attack while in bed with his mistress |
| 33% | MOOSE | 5 | Animal that can weigh up to 1,800 pounds and run 35 m.p.h. |
| 33% | GEESE | 5 | Birds that belong to the same family as ducks, and migrate in the fall season |
| 33% | NEPAL | 5 | Asian country that is home to Mount Everest and where you can partake in mountaineering |
| 33% | LEAN | 4 | "___ In: Women, Work, and the Will to Lead" (bestseller by Sheryl Sandberg) |
| 33% | GEN | 3 | Lead-in to X, Y and Z |
| 32% | WERENOT | 7 | Lead-in to "kidding" and "gonna take it" |
| 32% | DEMO | 4 | Lead-in to "gorgon" and "bats" to refer to the predatory humanoid creatures seen in "Stranger Things" |
| 32% | OMNI | 4 | Lead-in to present and potent |
| 32% | ALT | 3 | Lead-in to rock and weekly |
| 32% | NAB | 3 | Catch and run in |
| 32% | BRIDGES | 7 | Hollywood family name ... and what the answers to starred clues have in common |
| 32% | OLE | 3 | Her s___ purpose in life was to provide for herself and her family |
| 32% | STAUBACH | 8 | QB who led the Cowboys to victories in Super Bowls VI and XII |
| 32% | JONES | 5 | James Earl ___, actor and first African-American man to win the Tony Award in the Leading Actor category |
| 32% | RINSE | 5 | To lightly wash and soak in water |
| 32% | ONTHELINE | 9 | In jeopardy ... and where the first words of the answers to starred clues can be found |
| 32% | SHORTAGE | 8 | What hoarding can lead to |
| 32% | EGO | 3 | It can lead to arrogance |
| 31% | TOSTI | 5 | Paolo —, Italian composer and singing master to the British Royal Family knighted in 1908 |
| 31% | OUTOF | 5 | Lacking, and what can go with each word in the answers to starred clues |
| 31% | COLDFRONT | 9 | It ushers in lower temperatures ... and what the answers to starred clues can have |