| 100% | CPU | 3 | Heart of an H-P |
| 65% | CORE | 4 | Heart of an apple |
| 65% | CORE | 4 | Heart of an apple? |
| 59% | DIT | 3 | One-quarter of an H, in Morse code |
| 58% | ENRON | 5 | Company at the heart of an early 2000s scandal |
| 57% | PITAPAT | 7 | Sound of an excited heart |
| 55% | COMMANDCENTER | 13 | Heart of an operation, and a hidden feature of 20-, 26-, and 46-Across |
| 53% | CHAMBER | 7 | An atrium is a __ of the heart |
| 50% | OFFAL | 5 | Edible internal parts of an animal, such as the heart and liver |
| 50% | EERIE | 5 | Like an H.P. Lovecraft work |
| 50% | ASTRO | 5 | Wearer of an "H"-inscribed hat |
| 49% | ATRIUM | 6 | Upper chamber of the heart, once called an auricle |
| 48% | LOVECRAFT | 9 | H P —, science fiction and horror writer whose stories include The Case of Charles Dexter Ward |
| 47% | VENTRICLE | 9 | A cavity in an organ; the heart has two of them |
| 47% | TILLAKARATNE | 12 | H P —, Sri Lanka Test cricketer who hit an unbeaten 204 against West Indies in Colombo in 2001 |
| 46% | THREE | 5 | Number of hearts that an octopus has |
| 46% | NEWBY | 5 | P H —, author of 1969 inaugural Booker Prize-winning novel Something to Answer For |
| 46% | BOSC | 4 | Fruit variety whose name becomes that of an artist when you add an H to the end |
| 45% | SMOG | 4 | Subject of an exhaustive E.P.A. study? |
| 45% | CITY | 4 | Half of an E.P.A. rating |
| 44% | CITY | 4 | Half of an E.P.A. mileage rating |
| 44% | VERY | 4 | First part of an I.P. address? |
| 44% | CASE | 4 | "The ___ of Charles Dexter Ward," 1943 novel by H.P. Lovecraft about an alleged wizard |
| 44% | TESS | 4 | ___ Harper, actress nominated for an Oscar for her role in Crimes of the Heart |
| 44% | COEUR | 5 | Heart of France |
| 44% | COEUR | 5 | Heart of Paris |
| 44% | COEUR | 5 | Heart of Haiti |
| 44% | GEE | 3 | Heart of Pyongyang |
| 44% | COEUR | 5 | Heart of Paris? |