| 100% | JOANRIVERS | 10 | Late comedian who hosted "The Late Show" on Fox from 1986-1987: 2 wds. |
| 63% | JOANRIVERS | 10 | Comedian who was the first woman to host a late-night talk show on a major network: 2 wds. |
| 60% | JAYPHAROAH | 10 | Former "SNL" comedian who hosts the Fox game show "The Quiz With Balls": 2 wds. |
| 53% | STEPHENCOLBERT | 14 | Host of "The Late Show" who was once a correspondent on "The Daily Show": 2 wds. |
| 51% | CHELSEA | 7 | With 33-Across, comedian who hosted a late-night talk show on E! from 2007-2014 |
| 51% | LESLIEJONES | 11 | Former "Saturday Night Live" comedian who hosts the prime-time game show "Supermarket Sweep": 2 wds. |
| 50% | AHMADRASHAD | 11 | Former NFL wide receiver who hosted the game show "Tug of Words" from 2021-2022: 2 wds. |
| 50% | JIMMYKIMMEL | 11 | Late-night talk show host who voiced the father in "The Boss Baby": 2 wds. |
| 50% | JIMMYFALLON | 11 | "The Tonight Show" host who introduced these raps on "Late Night": 2 wds. |
| 49% | JAMESCORDEN | 11 | English late night show host who was the co-creator of BBC's Gavin & Stacey: 2 wds. |
| 48% | JONSTEWART | 10 | Comedian who was the host of "The Daily Show" till 2015, and has hosted 2 Grammy Award ceremonies: 2 wds. |
| 48% | JIMMYKIMMEL | 11 | Late-night talk show host who hosts the prime-time game show "Who Wants to Be a Millionaire": 2 wds. |
| 48% | CAROLBURNETT | 12 | Comedian and variety show host who was awarded the Mark Twain Prize in 2013: 2 wds. |
| 48% | JOHNOLIVER | 10 | Host of "Last Week Tonight" who was once a correspondent on "The Daily Show": 2 wds. |
| 48% | GEORGECARLIN | 12 | Comedian who hosted the first episode of "Saturday Night Live" on October 11, 1975 (2 wds.) |
| 48% | JAMESCORDEN | 11 | "The Late Late Show" host who voices the title character in 18-Across: 2 wds. |
| 48% | JOHNNYCARSON | 12 | American talk show host and comedian who hosted "The Tonight Show" for three straight decades: 2 wds. |
| 48% | MARCMARON | 9 | Comedian who hosts the "WTF" podcast: 2 wds. |
| 48% | KEITHHERNANDEZ | 14 | First baseman for the 1986 New York Mets who later appeared on "Seinfeld": 2 wds. |
| 47% | PATTONOSWALT | 12 | "Ghostbusters: Frozen Empire" actor who hosts the Amazon/Fox game show "The 1% Club": 2 wds. |
| 46% | CHRISHARDWICK | 13 | Comedian who hosts "Talking Dead" on AMC: 2 wds. |
| 46% | STEPHENCOLBERT | 14 | American late night show host who wrote the book "I Am America (And So Can You!)": 2 wds. |
| 46% | FLIPWILSON | 10 | Stand-up comedian who played Geraldine on his Emmy-winning variety show from 1970 to 1974: 2 wds. |
| 46% | CONANOBRIEN | 11 | Late-night host who moved to TBS after leaving "The Tonight Show": 2 wds. |
| 46% | JIMMYKIMMEL | 11 | American late night show host who was the co-host of Comedy Central's "The Man Show": 2 wds. |
| 46% | JAMESCORDEN | 11 | "The Late Late Show" host who voices Hi-5 in 32-Across: 2 wds. |
| 46% | REGGIEJACKSON | 13 | Right fielder who struck out 2,597 times from 1967 to 1987, first on the all-time list: 2 wds. |
| 45% | JAMESCORDEN | 11 | Former "The Late Late Show" host who plays No Name in "Smurfs": 2 wds. |
| 45% | JON | 3 | Comedian Stewart who hosted the "The Daily Show" from 1999 to 2015 |
| 45% | TOMARNOLD | 9 | Comedian who appeared on "The Best Damn Sports Show Period" in the 2000s (2 wds.) |