| 100% | STARTREK | 8 | Sci-fi series that released summer blockbusters in 2009, 2013, and 2016 |
| 33% | RIDE | 4 | “Bad Boys: ___ or Die” (Will Smith and Martin Lawrence blockbuster that was released in June, 2024) |
| 33% | DOCTORWHO | 9 | BBC sci-fi series that debuted in 1963: 2 wds. |
| 33% | FIREFLY | 7 | Sci-fi western series about space that blends space travel and outlaw adventures |
| 32% | GAMEOFTHRONES | 13 | HBO fantasy show that won Primetime Emmys for Outstanding Drama Series in 2015, 2016, 2018, and 2019 (3 wds.) |
| 32% | FRINGE | 6 | Sci-fi TV series starring John Noble that featured an animated episode in season 3 |
| 32% | EXPANSE | 7 | "The ___," American sci-fi series starring Steven Strait that aired its final season in 2022 |
| 31% | THEXFACTOR | 10 | Music competition series created by Simon Cowell that featured 53-Across as a host in 2012 and 2013 (3 wds.) |
| 31% | CARBON | 6 | "Altered ___," cyberpunk sci-fi TV series starring Chris Conner that is set in 2384 |
| 31% | IDOL | 4 | "American ___" (TV series that ended in April 2016) |
| 31% | AFTEREARTH | 10 | 2013 sci-fi film that features Will Smith and his real-life son Jaden: 2 wds. |
| 31% | AVATAR | 6 | Zoe Saldana and Sam Worthington movie of 2009, set in the 22nd century, that was released in traditional and 3-D formats |
| 30% | STARTREKPICARD | 14 | Sci-fi series starring 16-Across and 34-Across that debuted on CBS All Access on January 23, 2020 (3 wds.) |
| 30% | COVENANT | 8 | Sci-fi horror film directed by Ridley Scott, "Alien: ___," which is a sequel to "Prometheus," and released in 2017 |
| 30% | THEMASK | 7 | Comic book series that spawned films in 1994 and 2005 |
| 30% | DOCTORWHO | 9 | BBC sci-fi series in which 31-Across plays the 10th and 14th incarnations of the title character: 2 wds. |
| 30% | OUTLANDER | 9 | Multi-genre novel series that includes "Dragonfly in Amber" and "Voyager" |
| 29% | EXPANSE | 7 | "The ___," sci-fi drama series about space that focuses on a political conflict between Earth and other planets |
| 29% | OLYMPIANS | 9 | Those who compete in the Summer and Winter games |
| 29% | STARWARS | 8 | George Lucas sci-fi film series that debuted in 1977 (2 wds.) |
| 29% | FARGO | 5 | FX series that starred Kirsten Dunst and Patrick Wilson in season 2 |
| 29% | UFO | 3 | Sci-fi film with Alex Sharp and Gillian Anderson about events at the Cincinnati Intl. Airport, released straight to video in 2018 |
| 29% | EXPANSE | 7 | "The ___," sci-fi TV series starring Steven Strait that is set in a future where humans colonize the Solar System |
| 29% | WAKEMEUP | 8 | Mega hit and summer anthem for Avicii in 2013 |
| 28% | PACIFIC | 7 | "___ Rim," 2013 sci-fi film directed by Guillermo del Toro that features sea monsters and gigantic mechas |
| 28% | POV | 3 | PBS series that started in 1988 and has gathered 38 Emmys and 3 Oscars |
| 28% | SILO | 4 | Sci-fi TV series starring Rashida Jones that is set in a dystopian future where people exist only in a grain-storing tower |
| 28% | THEFORCE | 8 | Source of power in a series of blockbuster sci-fi films |
| 28% | JUNE | 4 | Month that's partly in spring and partly in summer |