| 100% | LORNEMICHAELS | 13 | Seth Meyers' executive producer on 24- and 29-Across: 2 wds. |
| 49% | WEEKENDUPDATE | 13 | Comedy news segment hosted by Seth Meyers on 24-Across: 2 wds. |
| 47% | EMILYMORTIMER | 13 | Actress who plays MacKenzie McHale, the executive producer on 37-Across: 2 wds. |
| 44% | NORMANLEAR | 10 | Executive producer of 32-Across and creator of the original version of the show: 2 wds. |
| 43% | JENNIFERLOPEZ | 13 | "On the Floor" singer who's an executive producer and judge on "World of Dance": 2 wds. |
| 39% | SHAWNCARTER | 11 | 18-Across and 29-Across rapper who turns 50 on December 4, 2019 (2 wds.) |
| 38% | SILKSONIC | 9 | "Leave the Door Open" R&B super-duo formed by 16- and 29-Across: 2 wds. |
| 38% | TRIPLECROWN | 11 | Batting feat that 17- and 29-Across achieved twice each: 2 wds. |
| 38% | DARKBLUE | 8 | Color on the spaces for 24- and 42-Across: 2 wds. |
| 37% | SHONDARHIMES | 12 | Creator, head writer, and executive producer of 18-Across (2 wds.) |
| 37% | NEILGAIMAN | 10 | Author of "The Sandman" graphic novels and 29-Across (2 wds.) |
| 37% | NINEMONTHS | 10 | 1995 rom-com starring Hugh Grant and 29-Across (2 wds.) |
| 37% | STILLALICE | 10 | 2014 drama starring Alec Baldwin and 29-Across (2 wds.) |
| 37% | NINEMONTHS | 10 | 1995 romcom starring Hugh Grant and 29-Across (2 wds.) |
| 36% | PATTONOSWALT | 12 | Comedian/actor of 14-Across and 29-Across who turned 50 on January 27, 2019 (2 wds.) |
| 36% | KNOCKEDUP | 9 | Comedy starring Seth Rogen and 47-Across (2 wds.) |
| 36% | LARRYDAVID | 10 | Brooklyn-born comedian who was an executive producer of 27-Across and 32/38-Across: 2 wds. |
| 36% | BLACKBIRD | 9 | Apple TV+ miniseries based on a true story starring 15-Across, 24-Across, and 30-Across (2 wds.) |
| 35% | LATENIGHT | 9 | Show on which Seth Meyers will replace Jimmy Fallon as host in 2014: 2 wds. |
| 35% | DAIRYCOW | 8 | Milk producer on a farm (2 wds.) |
| 35% | JURASSICWORLD | 13 | From executive producer Steven Spielberg, 2015 movie involving dinosaurs and humans : 2 wds. |
| 34% | ETCETERA | 8 | And so on (2 wds.) |
| 34% | COLEPORTER | 10 | American composer known for 17-Across and 29-Across (2 wds.) |
| 34% | STUCKWITHU | 10 | Single by Ariana Grande and 29-Across that debuted at No. 1 on the "Billboard" Top 100 in 2020 (3 wds.) |
| 33% | RESIDENTALIEN | 13 | Syfy series starring 15-Across, 29-Across, and 36-Across based on a Dark Horse Comics comic book (2 wds.) |
| 33% | ROBERTKIRKMAN | 13 | "Invincible" comic book author and one of the executive producers of 25-Across: 2 wds. |
| 33% | SANDRABULLOCK | 13 | "The Bird Box" actress and executive producer who stars in "Bullet Train" (2 wds.) |
| 32% | CHRISCORNELL | 12 | Late lead singer of 29-Across and Audioslave (2 wds.) |
| 31% | THUNDERFORCE | 12 | Superhero comedy starring Melissa McCarthy, 18-Across, and 29-Across (2 wds.) |
| 31% | FAMILYGUY | 9 | Animated TV series featuring the voices of Seth MacFarlane and 43-Across (2 wds.) |