| 100% | WIL | 3 | Actor Wheaton who played Wesley Crusher on "Star Trek: The Next Generation" |
| 75% | WIL | 3 | Actor Wheaton who played Wesley Crusher on "Star Trek: TNG" |
| 64% | DORN | 4 | Actor Michael who played Worf on "Star Trek: The Next Generation" |
| 64% | BRENT | 5 | Actor Spiner who plays Data on "Star Trek: The Next Generation" |
| 62% | LEVAR | 5 | Actor Burton who played Geordi La Forge on "Star Trek: The Next Generation" |
| 61% | WIL | 3 | Wheaton who played Wesley Crusher in Star Trek |
| 60% | PATRICKSTEWART | 14 | "X-Men" actor who played Captain Picard on "Star Trek: The Next Generation" (2 wds.) |
| 58% | WILWHEATON | 10 | "Star Trek: The Next Generation" actor who guest stars as himself on "The Big Bang Theory" (2 wds.) |
| 58% | MARINA | 6 | Actress Sirtis who played Counselor Troi on "Star Trek: The Next Generation" |
| 56% | PATRICKSTEWART | 14 | Actor who played Captain Jean-Luc Picard on "Star Trek: The Next Generation": 2 wds. |
| 55% | PATRICKSTEWART | 14 | "Star Trek: The Next Generation" actor who played Charles Xavier in "X-Men": 2 wds. |
| 54% | ENS | 3 | Wesley Crusher's rank on "Star Trek: The Next Generation" (Abbr.) |
| 53% | LEVARBURTON | 11 | "Star Trek: The Next Generation" actor who learns his ancestry on the 10th season of "Finding Your Roots" (2 wds.) |
| 53% | DORN | 4 | Michael who played Worf on "Star Trek: The Next Generation" |
| 53% | WILWHEATON | 10 | "Star Trek: The Next Generation" actor who voices amnesiac chef Earl Harlan, a character on 15-/51-Across: 2 wds. |
| 51% | WIL | 3 | "Star Trek: The Next Generation" actor Wheaton |
| 49% | TROI | 4 | Counselor Deanna on Star Trek: The Next Generation |
| 49% | DORN | 4 | Michael who played the son of Mogh on "Star Trek: The Next Generation" |
| 49% | WESLEYCRUSHER | 13 | "Star Trek: The Next Generation" ensign played by Wil Wheaton: 2 wds. |
| 49% | TROI | 4 | Picard's counselor on Star Trek: The Next Generation |
| 48% | WIL | 3 | Actor Wheaton of "Star Trek: The Next Generation" |
| 47% | WIL | 3 | Actor Wheaton of “Star Trek: The Next Generation” |
| 47% | CRUSHER | 7 | Wesley's last name on "Star Trek: The Next Generation" |
| 47% | WESLEY | 6 | Youngest Crusher in Star Trek: The Next Generation |
| 46% | SHATNER | 7 | William ___, actor who played Captain Kirk on "Star Trek: The Original Series" |
| 45% | WES | 3 | Ensign Crusher's nickname, on "Star Trek: The Next Generation" |
| 45% | WES | 3 | Beverly Crusher's son on "Star Trek: The Next Generation," for short |
| 45% | WORF | 4 | Klingon played by Michael Dorn on "Star Trek: The Next Generation" |
| 45% | DATA | 4 | Android played by Brent Spiner on "Star Trek: The Next Generation" |
| 44% | RIKER | 5 | Will played by Jonathan Frakes on “Star Trek: The Next Generation” |