| 100% | ELLEN | 5 | Astronaut Ochoa who was the first Latina in space |
| 86% | OCHOA | 5 | Astronaut Ellen who was the first Latina in space |
| 73% | ALAN | 4 | Astronaut Shepard who was the first American in space |
| 67% | RIDE | 4 | Astronaut Sally who was the first American woman in space |
| 67% | MAE | 3 | Astronaut Jemison who was the first Black woman in space |
| 67% | OCHOA | 5 | Astronaut Ellen who was the first Hispanic woman in space |
| 67% | MAE | 3 | Astronaut Jemison who was the first African-American woman in space |
| 60% | YURI | 4 | Cosmonaut Gagarin who was the first person in space |
| 60% | MAE | 3 | Jemison who was the first Black woman in space |
| 60% | JEMISON | 7 | Mae who was the first Black woman in space |
| 59% | LAIKA | 5 | Dog who was the first animal in space |
| 59% | SHEPARD | 7 | Alan who was the first American in space |
| 59% | SALLY | 5 | ___ Ride who was the first American woman in space |
| 59% | YURI | 4 | Gagarin who was the first human in outer space |
| 57% | ALEKSEI | 7 | Leonov who was the first man to walk in space |
| 55% | GLENN | 5 | Astronaut John who is the oldest person to have flown in space |
| 55% | YURI | 4 | Cosmonaut Gagarin who was the first human in outer space |
| 54% | MARTHA | 6 | Little ___, rabbit who was the first of her kind to be launched into space in 1959 |
| 52% | LORENA | 6 | Ochoa who was the first #1-ranked golfer from Mexico |
| 51% | LORENA | 6 | Ochoa who was the first No. 1 ranked golfer from Mexico |
| 50% | BELLS | 5 | "Jingle ___," iconic Christmas carol that was the first song played on musical instruments in space by Gemini 6 astronauts in 1965 |
| 49% | NEIL | 4 | First name in NASA's prestigious list of astronauts who have been to the moon |
| 49% | EILEEN | 6 | Collins who was the first woman Space Shuttle commander |
| 49% | RESNIK | 6 | Judith who was the second American woman in space |
| 49% | THIEL | 5 | Peter who was the first outside investor in Facebook |
| 49% | INDIRA | 6 | Gandhi who was the first female PM in India |
| 49% | ADA | 3 | Limón who is the first Latina to be Poet Laureate of the United States |
| 48% | OREE | 4 | Willie who was the first black player in the NHL |
| 48% | MEL | 3 | Allen who was the first host of "This Week in Baseball" |
| 47% | STU | 3 | Rasmussen who was the first openly transgender mayor in the U.S. |