| 100% | JERRYSEINFELD | 13 | Comedian who played a fictional version of himself on a sitcom about "nothing" (2 wds.) |
| 68% | RICHARDLEWIS | 12 | Stand-up comedian who plays a fictionalized version of himself on "Curb Your Enthusiasm" (2 wds.) |
| 60% | LARRYDAVID | 10 | "Seinfeld" co-creator who plays a fictionalized version of himself on "Curb Your Enthusiasm" (2 wds.) |
| 60% | WANDASYKES | 10 | Stand-up comedian who plays a fictionalized version of herself on "Curb Your Enthusiasm" (2 wds.) |
| 59% | NYE | 3 | "Science Guy" Bill who plays a fictional version of himself on "Blindspot" |
| 46% | LAURIEMETCALF | 13 | Actress whose real-life daughter played a younger version of her character on "Roseanne": 2 wds. |
| 46% | PATRICKHARRIS | 13 | Neil ___, actor who made a cameo in "Harold & Kumar go to White Castle" by playing a fictionalized version of himself: 2 wds. |
| 45% | LARRYDAVID | 10 | Actor and comedian who created HBO's comedy series "Curb Your Enthusiasm" and stars in it as a fictionalized version of himself: 2 wds. |
| 44% | CAROLBURNETT | 12 | Emmy-winning comedian who played a clumsy woman with a guardian angel on "The Twilight Zone": 2 wds. |
| 44% | DANADELANY | 10 | "China Beach" actress who played a medical examiner on "Body of Proof": 2 wds. |
| 44% | KUMAILNANJIANI | 14 | "Silicon Valley" actor who starred as a semifictional version of himself in 2017's "The Big Sick": 2 wds. |
| 44% | PETEDAVIDSON | 12 | Comedian on 29-Down who plays Scott in "The King of Staten Island": 2 wds. |
| 43% | GEORGELOPEZ | 11 | Mexican-American comedian who starred on a self-titled sitcom: 2 wds. |
| 43% | PATTYDUKE | 9 | Late actress who played identical cousins on a 1960s sitcom: 2 wds. |
| 43% | RICHARDDAWSON | 13 | "Family Feud" host who was a regular panelist on the 1970s version of "Match Game": 2 wds. |
| 43% | ANDYSAMBERG | 11 | Former "SNL" comedian who stars on a sitcom set in an NYPD precinct: 2 wds. |
| 43% | HUGHDANCY | 9 | "Confessions of a Shopaholic" actor who plays Will Graham on NBC's "Hannibal": 2 wds. |
| 43% | WILLSMITH | 9 | Actor who starred as a fictionalized version of himself in the hit TV series "The Fresh Prince of Bel-Air": 2 wds. |
| 43% | GEMINIMAN | 9 | 2019 Ang Lee film about a sniper who is targeted by a young clone of himself: 2 wds. |
| 43% | FANNIEFLAGG | 11 | Red-headed comic actress who was a regular panelist on the 1970s version of "Match Game": 2 wds. |
| 43% | JOHNMULANEY | 11 | Stand-up comedian who guest-stars as Stevie on a 2023 flashback episode of "The Bear": 2 wds. |
| 42% | DAMIANMCGINTY | 13 | Irish singer who played Rory Flanagan on "Glee" and was a member of 32-Across: 2 wds. |
| 42% | BRETTSOMERS | 11 | Saucy-tongued wife of Jack Klugman who was a regular panelist on the 1970s version of "Match Game": 2 wds. |
| 42% | SEINFELD | 8 | TV series created by and starring stand-up comedian Jerry as a fictional version of himself |
| 41% | ANNAFARIS | 9 | Actress who played Christy Plunkett on the first seven seasons of the CBS sitcom "Mom": 2 wds. |
| 41% | CARLOSVALDES | 12 | Actor who plays Cisco Ramon on "The Flash" which is a part of the Arrowverse: 2 wds. |
| 41% | JERRYSEINFELD | 13 | The lead character from "Seinfeld", who is a semi-fictional version of the actor who plays the role and goes by the same name: 2 wds. |
| 41% | YARASHAHIDI | 11 | "The Sun Is Also a Star" actress who plays Zoey on the Freeform sitcom "Grown-ish": 2 wds. |
| 41% | CRASHING | 8 | TV series created by comedian Pete Holmes that features a fictional version of himself |
| 41% | COSMOKRAMER | 11 | Character played by Michael Richards in a sitcom about "nothing" (2 wds.) |